162 LIFESTYLE COSMETICS
xanthin 3% cream, the biophysical parameter SEW was monitored in the volunteers’ periocular area using a Visioscan®
17.0 VC 98 USB (Courage+Khazaka
electronic GmbH, Germany). SEW was calculated from the mean number and the mean width of the horizontal and vertical wrinkles (calculation lines). Lower SEW values indicate fewer wrinkles. Figure 11 shows the downwards evolution of the SEW values over the 56 days of the experiment, achieving an average decrease of 13% (p = 0.000) by day 56. SEW reduction was observed in 88% of volunteers. Figure 12 shows the visible decrease in wrinkles for two volunteers at three time points: 0, 28 and 56 days. The use of bicosome-xanthin skin superfood boosts skin function and repairs the most significant signs of ageing.
Clinical evaluation In parallel to the measurements above, the non-comedogenic evaluation of the product was carried out by the dermatologist at the beginning of the study (day 0) and after 28 and 56 days of the experiment. The appearance of lesions such as open comedones, closed comedones, papules, pustules, cysts and nodules was evaluated. At the end of the study of continuous use, bicosome-xanthin was classified as non-comedogenic.
Statistical studies Linear mixed-effect models (LMM) were fitted to evaluate the efficacy of the treatment over time. Parameters were interpreted with reference to the baseline time. In the case of cell renewal efficacy, the control area was taken as the reference. The significance value established was 0.05 (95% confidence interval).
16.5 16.0 15.5 15.0 14.5 14.0 Day 0 Day 14 Day 28 Day 56 * *
13% average improvement
*
Figure 11: Anti-wrinkle effect. Average SEW parameter ± SE at different experimental times. (n=20), * = p value < 0.05.
Conclusion
Bicosome-xanthin combines two innovative, eco-friendly technologies to produce an extraordinary skin superfood. The technical excellence of the product relies on its capacity to incorporate and stabilise the nutrients of a microalgae extract in an advanced skin delivery technology that is capable of stabilising and transporting them to deep skin layers, so they can be used by the skin. The result of this combination is a highly efficient ingredient for skin detox and ageing repair, especially recommended for use in urban centres, where modern lifestyle requires a special skincare strategy. Bicosome-xanthin proved to be effective in boosting the skin’s defences against pollution and electronic light and visibly improving the skin’s
antioxidant power, cell renewal, barrier function, firmness, brightness and wrinkles, as measured in vivo. Bicosome-xanthin proves that when cosmetic development is driven by science, the combination of effective and natural is possible.
PC
References 1 Marion D,
et.al. Clinical effects of an oral supplement rich in antioxidants on skin radiance in women. Clin. Cosmet. Investig. Dermatol. 2016;9:315–324.
2 Luis García J.
et.al. Presente Y Futuro Del Cultivo De Las Microalgas Para Su Uso Como Superalimentos. Mediterraneo económico 2018; 333–350
3 Davinelli S
et.al. Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review. Nutrients 2018;10(522):1–12.
4 Huangfu J, et al. Antiaging effects of astaxanthin-rich alga Haematococcus pluvialis on fruit flies under oxidative stress. J. Agric. Food Chem. 2013; 61:7800–7804.
5 Shah M, et al. Astaxanthin-Producing Green From Single Cell to High Value Commercial Products. Frontiers in plant Science 2016; 7 (531):1-28.
6 Fernánndez E. et al. A rhenium tris-carbonyl derivative as a model molecule for incorporation into phospholipid assemblies for skin applications. Colloids Surfaces B Biointerfaces 2015; 131:102–107.
7 Lefebvre MA et al. Evaluation of the impact of urban pollution on the quality of skin: A multicentre study in Mexico. Int. J. Cosmet. Sci. 2015; 37: 329–338.
8 Antunes A. et al. Effect of blue light irradiation on the stability of phospholipid molecules in the presence of epigallocatechin-3-gallate. Colloids Surfaces B Biointerfaces. 2019; 177: 50–57.
Figure 12: Visioface® macro photographs of volunteers showing the evolution of wrinkle repair of two volunteers in four time points. PERSONAL CARE EUROPE
9 Vázquez-González ML
et.al. Bicosomes as biomimetic fillers to improve the organisation of the skin lipid structures. Househ. Pers. Care Today. 2017;12: 25–26.
April 2019
SEW
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