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BIOTECHNOLOGY


65


Multi-omic skin protection with an ecosystem active


Clara Vigo, Elizabeth Escudero, Silvia Benito, David Manzano – Provital ABSTRACT


Just as the world operates as a vast interconnected network on a global scale, in the intricate and complex fabric of an ecosystem, plants, animals, and microorganisms maintain various interkingdom symbiotic relationships that are essential to the balance and vitality of the entire natural system. In a context of green technology


development, respect for nature and the pursuit of well-being, Provital introduces its groundbreaking ingredient Shiloxome™, the first real ‘ecosystem ingredient,’ which brings together age-defying benefits while protecting the skin through a proven multi-omics approach. Crafted through the first-of-its-kind


Triplobiome™ technology, this active ingredient stems from isolating the endophytic yeast Kwoniella mangroviensis, found within the protective bark of the cork oak (Quercus suber). Thanks to such symbiotic origin, Shiloxome stands as an unparalleled shield, empowering the skin to adapt, thrive, and safeguard itself.


In today’s dynamic global landscape, the world functions as a vast, interconnected network driven by extensive data exchanges. Technology, trade, and communication weave an intricate web of interdependence, fostering a collective consciousness. This interconnectedness is evident in the


ripple effect of environmental, economic, and social events, emphasizing the need for a collaborative mindset to address global challenges, as actions in one part of the world resonate across our shared planet. In the intricate fabric of ecosystems, plants, animals, and microorganisms engage in vital interkingdom symbiotic relationships, essential for overall balance and vitality. Endophytic relationships, in which microorganisms reside within plant tissues, contribute significantly to ecosystem health by playing key roles in nutrient cycling, disease resistance, and stability.1 Endophytes, nestled within plants, not


only bolster growth, but also craft bioactive compounds, offering an eco-friendly alternative to conventional sourcing methods. Therefore, exploring this interconnectivity


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between kingdoms not only unveils the delicate dynamics of the natural world, but also opens a wide array of new possibilities in the cosmetics field.


Interkingdom symbiosis as a new era for beauty development With the persistent goal of maintaining biodiversity – key for ecosystem balance – and preventing the use of the current huge plant biomass needed to obtain natural active compounds for cosmetic purposes, Provital presents its breakthrough biotech platform that uses plant endophytes as a sustainable and effective source to produce new natural active ingredients (Figure 1). The first of these new ‘ecosystem


ingredients’ is a 100% traceable, eco- responsible, and biotechnologically ferment derived from the endophytic yeast Kwoniella mangroviensis. Isolated from within the cork oak’s protective bark, K. mangroviensis serves as an unmatched shield for the skin. With its symbiotic origin, it empowers


the skin to adapt, survive, and protect itself, mimicking the protective function of the


cork oak bark. These new active harnesses this protective power to create a well- ageing ingredient, offering anti-pollution and restructuring properties for the skin’s protective barriers.


Beyond barrier care with a multi- ome skin protection The growing interest in holistic skin wellness has prompted a transition towards strengthening the skin barrier in a more comprehensive manner.2


This shift is especially vital for mature


skin, which experiences notable changes, resulting in heightened dryness, sensitivity, and a compromised lipid barrier. Consequently, innovative solutions for lipid


barrier care must arise as a crucial intervention, serving not only to maintain skin integrity, but also to promote well-ageing advantages. In this context, Provital goes above and


beyond standard barrier care for well-ageing consumers. As its lipidomic study proves, this new active introduces innovative lipid- enhancing mechanisms for the stratum corneum, actively replenishing the lipid barrier, reinforcing moisture retention, and improving


April 2024 PERSONAL CARE


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