NATURALS
135
Complex polysaccharides derived from torula yeast
Masayuki Ito, Yusuke Fukuda, Yasuhito Yokoi, Tomoko Ohtsu and Tadayoshi Katsumata - Mitsubishi Corporation Life Sciences
Mitsubishi Corporation Life Sciences has succeeded in producing a new complex polysaccharide from yeast cell walls that had been discarded after fermentation. Torula yeast (Cyberlindnera jadinii) is a yeast widely used in the production of seasonings and other products that impart flavour and richness through fermentation, but many of the yeast cells produced in the manufacturing process are not utilized and are discarded. We isolated complex polysaccharides from
the cell walls of this discarded yeast cell by alkaline washing/enzymatic treatment. The polysaccharide complex is a white to light yellow powder, containing about 40% β1,3-1,6 glucan, which is well known for its cell activating action, and about 30% mannan and other polysaccharides.1 Although originated from yeast with
sufficient food history, safety testing results AMES test, in vitro skin irritation test, in vitro eye irritation test, human patch test, and RIPT (human cumulative irritation) test were conducted, all of which showed negative results. When the effects on the skin were evaluated, high moisturizing and texture (kime) improvement effects were observed. Measurement of the antifreeze water of this
polysaccharide suggested that it has a moisture retention property equivalent to that of sodium hyaluronate. On the other hand, the aqueous solution of this polysaccharide complex, unlike general polysaccharides, has the following unique properties: the solution is not viscous, weak surfactant activity is observed, and it has
film-forming ability. Furthermore, since the improvement effect
of damaged hair was also confirmed, it can be used in a wide range of cosmetics from skin care to hair care.
The benefits of torula yeast Yeast is a non-filamentous, unicellular eukaryote with a diameter of 5-10 µm, whose cell wall is constructed from polysaccharides, mainly glucans and mannans. Yeast is closely related to our food culture, including the fermentation of bread and the
production of alcohol. In addition, many of the seasonings that we usually eat - such as umami used in Japanese cuisine - are produced by fermentation, which is the life activity of microorganisms such as yeast. On the other hand, yeast bodies produced in the manufacturing process of seasonings are not utilized, and many of them are discarded. In recent years, there has been a growing demand for products that add new value to cosmetic ingredients by upcycling various unused resources. In May 2023, we successfully developed and launched a cosmetic ingredient with the product name Gluca Moist, hereafter the torula yeast polysaccharide, based on an unutilized yeast. In this article, we describe the characteristics of the torula yeast polysaccharide, the results of clinical trials, and its further use in hair care. Torula yeast (Cyberlindnera jadinii) is a
yeast with a long food history that is used to produce flavour and rich seasonings necessary for Japanese cuisine. In the production of these fermented seasonings, the torula yeast bodies used were discarded in large quantities after the seasonings were extracted. We developed an upcyclable cosmetic
www.personalcaremagazine.com Figure 1: Properties of Gluca Moist
ingredient by extracting the polysaccharides contained in the yeast cell walls. The torula yeast polysaccharide is produced by collecting torula yeast after seasoning extraction and purifying the complex polysaccharides from
April 2024 PERSONAL CARE
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