FORMULATING FOR MILDNESS 73 D0 D28


sensitive, reactive, atopic-prone skin. After 4 weeks application of the cream containing Activys Red-Out a significant improvement in red spots (18%) and red spots area (21.2%) was observed compared to placebo cream. Pictures taken before (D0) and after


(D28) treatment with Activys Red-Out illustrate the expected benefits of regular use of a product containing the active ingredient and a significant improvement in the visible signs of inflammation and general comfort of the skin.


PC


References 1 Spergel JM, Paller AS. Atopic dermatitis and


the atopic march. Journal of Allergy and Clinical Immunology 2003; 112 (6), Supplement, S118-S127.


2 Goindi S, Kumar G, Kumar N, Kaur A. Development of Novel Elastic Vesicle-Based Topical Formulation of Cetirizine Dihydrochloride for Treatment of Atopic Dermatitis. AAPS PharmSciTech 2013; 14(4).


3 Fonacier LS, Dreskin SC, Leung DYM. Allergic skin diseases. J Allergy Clin Immunol. 2010;125(2):S138–49.


4 Burri L, Hoem N, Banni S, Berge K. Marine Omega-3 Phospholipids: Metabolism and Biological Activities. Int. J. Mol. Sci. 2012; 13, 15401-15419.


5 Nackaa F, Cansella M, Méléardb P, Combe N. Incorporation of -Tocopherol in Marine Lipid- Based Liposomes: in Vitro and in Vivo Studies. Lipids 2001; 36(12)


6 Jurenka JS. Anti-inflammatory Properties of Curcumin, a Major Constituent of Curcuma longa: A Review of Preclinical and Clinical Research. Alternative Medicine Review. 2009; 14(2).


7 Grimm T, Schäfer A, Högger P. Antioxidant activity and inhibition of matrix metalloproteinases by metabolites of maritime pine bark extract (Pycnogenol). Free Radical Biology and Medicine. 2004; 36(6): 811-822.


8 D'Andrea G. Pycnogenol: a blend of procyanidins with multifaceted therapeutic


April 2018 Patented


Globally compliant


Eco-designed


The high potential of Nectarobiota® The floral nectar microbiota, called Nectarobiota®


Figure 4: Reduction of inflammatory markers. Synergy between actives and encapsulation system


sustainable alliance


ECOBIOTYS® From Nectarobiota®


the power of bio-inspiration , stands out


by its high regulating capacity ensuring the plant’s defense, development and regeneration. SILAB specifically isolated Metschnikowia reukaufii, a dominant yeast of floral nectar to develop ECOBIOTYS®


, an active that regulates skin ecology. in vitro efficacy


SILAB’s expertise in microbiota - restores the functionality of the skin’s immune barrier - rebalances the ecology of mature skin, acting on bacterial diversity and abundance


in vivo benefits


- improves the quality of the skin barrier - enhances the radiance of the complexion


e MATURE SKIN ECOLOGY


to skin microbiota:


www.silab.fr engineering natural active ingredients


PERSONAL CARE EUROPE


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