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104 ANTI-AGEING


the active oil serum showed a statistically significant improvement of the skin roughness of the forehead area. Regarding the wrinkle depth parameter, the active group showed a statistically significant decrease compared to initial time.


‘Tech neck’ improvement after 28 days of treatment Currently, digital generations spend a lot of time on their smartphones daily, keeping more and more connected with the news and society. All this time implies an inclination of the head towards the screen, leading to the appearance of premature neck folds, also known as ‘tech neck’. To evaluate the ‘tech neck’ improvement,


a clinical evaluation was carried out by a dermatologist at initial time and after 28 days of product application. The dermatologist evaluated the neck folds using a 0-4 scale (0 no improvement, 4 remarkable improvement). The same expert graded the same subjects throughout the course of the study. As shown in Figure 7, treatment with the new


active ingredient improved the appearance of neck folds by 60% after 28 days of treatment, which was 10% more than the placebo group. The volunteer images before and after the treatment are an example of how the active peptide smooths the horizontal lines under the chin.


Volunteers’ opinion and feelings after the treatment Finally, we carried out a self-assessment questionnaire to know the opinion of the volunteers regarding the efficacy of the product after 28 days of product use. As shown in Figure 8, volunteers who applied the active oil serum observed better results in their skin than the group who applied the placebo oil serum. They observed an improvement of firmness,


better skin texture with smoother skin, and a reduction of the expression wrinkles showing minimized fine lines and an improvement of the overall facial appearance.


AFTER USING THE PRODUCT, I’VE OBSERVED... Placebo ■ 0.8% new active ingredient ■


Improved skin texture


Improved skin firmness


100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0%


Smooth skin Expression wrinkles


Reduction of expression wrinkles


have diminished without


affecting the natural beauty of my facial expressions


B A


70 60 50 40 30 20 10 0


28 days 0 days 28 days Placebo ■ 0.8% new active ingredient ■


60% ****


10%


Figure 7: A. Improvement in neck folds after 28 days of treatment (****p<0.0001 versus initial time) versus placebo. Student’s t test was used after checking the normality distributions by a Shapiro- Wilk test. B. Images of a volunteer before and after 28 days of treatment with the active ingredient


Additionally, their feelings were more


positive after the treatment. They noticed the treatment helped them prevent the signs of ageing with an improvement of expression wrinkles, but without affecting their natural facial expressions. This observation made them feel better about themselves, happier and more confident with their smiles.


Conclusion The new active ingredient has been shown to improve the skin of the crow’s feet area during a smile expression. Furthermore, it minimizes


the appearance of expression wrinkles on the areas of greatest concerns among young generations, such as forehead, crow’s feet, nasolabial folds and neck lines. The efficacy of this peptide has shown to make users feel happier with their skin, leading to greater self- confidence in their daily life. In conclusion, the new active ingredient is


ideal for oil-based and makeup formulations aiming to prevent the emergence of expression wrinkles that might appear in the future, without negatively affecting beautiful facial expressions.


AFTER USING THE PRODUCT, I FEEL... Placebo ■ 0.8% new active ingredient ■


I’m preventing the signs of aging on facial skin


100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0%


My skin looks better


Improved overall facial appearance


Minimized fine lines


I feel confident the way I look when taking a selfie


I feel more confident with my smile


Figure 8: A. Positive answers of the volunteers in what they observed on their skin after 28 days of treatment versus placebo. B. Positive answers of the volunteers in how they felt after 28 days of treatment versus placebo


PERSONAL CARE April 2023 www.personalcaremagazine.com


PC


I feel better about the way I feel about myself


I feel hapier with the way my facial skin looks


Average improvment in neck fold (%)


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