126 ANTI-AGEING
Preventive and curative approaches - exposome management As discussed above, ageing is a multifactorial process influenced by both external aggressors and intrinsic factors, making it essential to adopt a dual approach that not only protects the skin from damage but also actively reverses existing signs of ageing. A preventive skin care approach focuses on
protecting the skin from premature ageing and damage before visible signs appear. This strategy involves using active ingredients and skin care routines that help strengthen the skin’s natural defences, maintain its barrier function, and counteract environmental and intrinsic stressors. Key aspects of a preventive skin care
approach include: ■ Antioxidant protection (e.g. vitamin C, vitamin E, polyphenols) to neutralize free radicals and prevent oxidative stress. ■ Sun protection (broad-spectrum SPF) to shield against UV-induced damage, one of the primary causes of premature ageing. ■ Hydration and barrier support (hyaluronic acid, ceramides, niacinamide, biomimetic ingredients) to maintain skin moisture and resilience. ■ Lifestyle and exposome management, considering factors like diet, sleep, circadian rhythm, stress, pollution, physical activity, and hormonal balance that influence skin health over time. Curative strategies, on the other hand, aim
to repair and rejuvenate skin affected by time and external assaults. Advanced skin care formulations can target oxidative damage, restore the extracellular matrix (ECM), modulate pigmentation, support epidermal renewal, and rebalance the skin microbiome to promote a healthier, more youthful complexion. At Barentz, we embrace exposome
management as a cornerstone of modern skin care, addressing a wide range of environmental and biological influences that impact skin health over time. Building on these principles, Barentz Personal Care introduced in 2024 the ‘ExpoCare Multi-Use Collection’, a forward- thinking skin care concept designed to counteract the biological changes induced by the exposome that contribute to visible ageing. This comprehensive collection consists of innovative formulas, each meticulously designed to address key ageing pathways: ■ Microbiome balance, ensuring the skin microbiota remains diverse and resilient ■ Barrier function reinforcement, preventing dehydration, nourishing and replenishing skin lipids ■ Inflammation control, soothing and anti-senescence effect, minimizing chronic inflammation that accelerates skin ageing ■ Melanogenesis regulation, reducing hyperpigmentation and promoting an even skin tone ■ ECM support, collagen boosting, improving dermal structure, elasticity, and firmness ■ Epidermal renewal stimulation, enhancing cellular turnover for a fresh, youthful appearance By integrating scientific innovation with a deep understanding of skin biology, Barentz’s
PERSONAL CARE April 2025
‘ExpoCare Multi-Use Collection’ offers a multifaceted solution for consumers looking to both protect and restore their skin, ensuring a comprehensive approach to skin longevity and well-being.
Innovative Ingredients: Harnessing Cutting- Edge Actives for Longevity and Biohacking The development of innovative cosmetic ingredients plays a crucial role in promoting skin longevity by targeting key biological processes associated with ageing. Advanced bioactive compounds help protect and restore the skin’s intrinsic capacity, mitigating oxidative stress, glycation, inflammation, and cellular damage. One of the most well-known longevity- boosting ingredients is resveratrol, a potent polyphenol that activates the expression of sirtuins, also known as longevity proteins. Sirtuins play a crucial role in cellular repair, DNA stability, and energy metabolism, ultimately helping to slow the visible signs of ageing. Other essential polyphenols, as well as
vitamins A and E, contribute to replenishing the skin’s antioxidant pool. By counteracting oxidative stress, these compounds help limit the oxidation of DNA, lipids, and proteins, thereby reducing cellular damage and delaying the skin’s ageing process. Additionally, they help inhibit glycation, a process in which sugar molecules bind to proteins and lipids, leading to structural degradation and loss of skin elasticity. Niacinamide (Vitamin B3) and NAD+
(Nicotinamide Adenine Dinucleotide) are also critical in skin biohacking strategies. These molecules are essential for mitochondrial function, cellular energy production, and sirtuin activation. By improving mitochondrial efficiency, niacinamide and NAD+ support cellular repair mechanisms, enhance skin barrier function, and promote a more youthful complexion. Another key longevity ingredient is carnosine (or its derivative, carcinine, an even more
stable and efficient form), acting as both an antioxidant and an anti-glycation agent. It helps protect collagen and elastin fibres from degradation while neutralizing free radicals, preserving skin firmness and resilience over time. By incorporating these innovative bioactive
ingredients, modern skin care formulations can offer targeted, science-backed solutions to protect, repair, and optimize the skin’s longevity potential, ensuring a youthful, radiant appearance for years to come.
Moving forward By understanding intrinsic capacity, promoting vitality, and adopting innovative strategies, we can pave the way for a future where longevity is not just about living longer but living better. At Barentz Personal care, we are committed to bringing innovative solutions that match our customers’ needs. In 2025, we are introducing the powerful concept of biohacking, supported by the science of longevity to skin care helping to protect, repair and rejuvenate the skin. Our ‘Skin’telligent Beauty Collection’ features
ten cutting-edge formulations, each composed of at least 95% ingredients of natural origin, designed to help the skin express its full potential, these innovative formulations combine advanced textures with carefully selected ingredients that provide well-being and bio-mimicking effect. This approach enhances natural optimization, leveraging breakthrough techniques such as AI, green chemistry, vectorization, epigenetic science, and biotechnology.
PC
References 1. MacNee W, Rabinovich RA, Choudhury G. Ageing and the border between health and disease. European Respiratory Journal. 2014; 44(5): 1332-1352
2. Lopez-Otin C, Blasco MA, Partridge L et al. The hallmarks of aging. Cell. 2013; 153: 1194–1217
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