ANTI-AGEING
(WHO) has defined “healthy ageing,” as “the process of developing and maintaining the functional ability that enables well-being in older age.” This concept shifts the focus from merely increasing lifespan to enhancing the quality of life through functional and intrinsic capacities.
Understanding intrinsic capacity (IC) Intrinsic capacity (IC) is a cornerstone of healthy ageing. According to the WHO, IC is “the composite of all the physical and mental capacities that an individual can draw on” at any point in time. It emphasizes a function- focused perspective rather than a disease- oriented approach to ageing. The current framework identifies five pivotal
domains of IC: ■ Locomotion: Physical mobility and strength. ■ Cognition: Mental acuity, memory, and problem-solving. ■ Vitality: Underlying physiological capacity, including energy and metabolism. ■ Psychology: Emotional well-being and resilience. ■ Sensory: Vision, hearing, and other sensory functions.
Vitality: The core domain of intrinsic capacity Among the five domains, vitality capacity has emerged as a central determinant of IC. Vitality is rooted in the body’s physiological systems, encompassing hormonal function, energy metabolism, and cardiorespiratory capacity. Research suggests that vitality is influenced
by: ■ Hormonal function: Regulating processes like metabolism and growth. ■ Energy metabolism: Efficient energy production and usage. ■ Cardiorespiratory function: Maintaining oxygen delivery and circulation. Additional factors such as nutrition, body
composition, muscle endurance, respiratory health, and psychological well-being also play roles in determining vitality capacity. Furthermore, emerging evidence from
geroscience highlights the importance of cellular senescence, DNA integrity, and intercellular communication as physiological attributes underlying vitality.
Longevity: Beyond lifespan Longevity refers to living a long life beyond the species-specific average age at death. However, longevity should not merely be about extending years but enhancing the quality of those years. This is where the concept of healthy ageing
intersects with longevity. Strategies to promote longevity must address the root causes of ageing and mitigate their effects. The biological hallmarks of ageing can
provide a robust framework for understanding and addressing ageing-related challenges. These hallmarks include genomic instability, telomere attrition, epigenetic alterations, mitochondrial dysfunction, chronic inflammation, dysbiosis, stem cell exhaustion, among others (Figure 3).2 The proposed twelve hallmarks of ageing
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Figure 3: The hallmarks of ageing
are grouped into three categories. The primary hallmarks can be considered to be the primary causes of cellular damage. The antagonistic hallmarks are responses to the damage. These responses initially mitigate
the damage, but eventually, if chronic or exacerbated, they become deleterious themselves. Last, there are integrative hallmarks that are the end result of the previous two groups of hallmarks and are ultimately responsible for the functional decline associated with ageing. The definition of hallmarks of ageing may
contribute to building a framework for future studies on the processes of ageing as well as for designing strategies to improve human health span. In the personal care industry, active ingredients aimed at these mechanisms can potentially extend healthy longevity to the skin. Hopefully, combined approaches will allow better results.
Strategies to extend skin longevity Skin, the largest organ of the body, is highly susceptible to intrinsic ageing and environmental stressors. Prolonging skin longevity requires a multi-faceted approach:
Personalized skin care solutions: tailoring skin care products to individual needs At Barentz, our marketing team is dedicated to analyzing emerging trends and evolving consumer expectations to ensure that we provide our customers with innovative, tailor-
made solutions. Understanding that no two skin types are alike, we believe in a holistic approach to skin care innovation, combining market insights, scientific research, and advanced formulation technologies to develop the most effective products. Our marketing department works hand in
hand with our R&D formulation laboratories, acting as key drivers of innovation. By identifying new opportunities in the beauty industry and collaborating closely with our formulators and product managers, we help create high-performance, next-generation skin care solutions that align with the growing demand for personalization. The future of skin care is moving towards
ultra-personalization, with groundbreaking advancements in smart beauty devices, AI-driven skin diagnostics, and formulation customization. Innovative tools such as skin scanners, genetic profiling, and microbiome analysis allow brands to develop hyper- targeted skin care regimens tailored to each individual’s unique needs. This shift represents a major market evolution, empowering consumers to take a more proactive and scientific approach to their skin care routines. By leveraging high technologies and
premium active ingredients, Barentz is committed to supporting its customers in the development of personalized, results-driven skin care solutions, ensuring a perfect synergy between science, innovation, and individual beauty needs.
April 2025 PERSONAL CARE
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