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14 NEWS 12


Lubrizol ‘extends anti- wrinkle effects of Botox’


A clinical study by Lubrizol has found the combination of its Argireline Amplified peptide and Botox type-A (BTA) injections can keep wrinkles at bay for nearly eight weeks longer than BTA alone. In the recent study, 45


Caucasian volunteers, both male and female, aged between 35 and 60, received 50 UI BTA injections in the crow’s feet, frown lines, and forehead areas. They also applied a cream


containing 5% Argireline Amplified peptide solution or a placebo cream to their entire face twice daily for four months. Researchers utilized 2D and 3D facial imaging to monitor changes


in wrinkle visibility, skin roughness, and wrinkle length in areas such as crow’s feet, frown lines, and the forehead. Results showed that after one,


three and four months, participants who received the active peptide combination treatment exhibited significantly fewer wrinkles compared to those who received BTA and a placebo. This combination treatment


extended the wrinkle-free period by almost eight weeks longer than BTA alone. “The synergy between BTA and


Argireline Amplified peptide meets the growing demand for effective, longer-lasting dermo-aesthetic solutions, allowing consumers to make fewer trips to the clinic and spend more time enjoying the benefits of smooth, youthful skin,” said Lubrizol.


Cellugy unwraps biofabricated cellulose-based product The product is the first in a


Cellugy has taken the wraps off the first commercial skin care product made using its EcoFLEXY biofabricated cellulose-based material. The Danish biotech outfit has partnered with skin care startup Bioli, which has launched Moisturizing and Protecting Day Cream. Cellugy and Bioli’s collaboration


results in a product that pairs bioactive, antioxidizing skin care with 100% biodegradable, fossil-free ingredients (including packaging) in a high-performance solution with low environmental impact. Moisturizing and Protecting Day


Cream also incorporates Cellugy’s EcoFLEXY as a biobased rheology


modifier to achieve a high-quality texture.


series, with more to follow soon. Additionally, Cellugy is in discussions for EcoFLEXY distribution deals covering 11 key cosmetics markets in the EU and the US. Cellugy aims to scale up


production to commercial volumes, targeting a full commercial launch in April. “It’s fantastic to see EcoFLEXY


put to use as an ingredient in a commercially available product for the first time. We’re also very happy to support Bioli’s unique concept as we share a common vision for a more sustainable future in skincare,” said Dr. Isabel Alvarez- Martos, CEO and co-founder of Cellugy. “In EcoFLEXY, we’ve developed a solution that’s now ready to be adopted by manufacturers looking for the high-performance of petrochemical rheology modifiers with the sustainability benefits of biobased options,” she added.


Givaudan gets tough on dandruff with DandErase


Givaudan Active Beauty has launched DandErase, a botanical active designed to eradicate dandruff and restore scalp health. The molecule is crafted by


green fractionation from the petals of Crocus sativus L., commonly known as saffron, sustainably sourced in Morocco. Dandruff is a widespread


scalp condition, resulting in oily yellow flakes, itching and often, inflammation. Malassezia overgrowth is a


PERSONAL CARE April 2025


key causal factor for this condition. Although naturally present in the skin microbiota, environmental factors can upset this balance, triggering the onset of dandruff. DandErase addresses both


the root causes and symptoms of


dandruff with a comprehensive mode of action by: inhibiting the growth ofMalassezia; reducing inflammation and erythema; mitigating itching and scalp discomfort; restoring the barrier function of the skin and scalp; and balancing the microbiome for long- lasting anti-dandruff effects. Clinical trials demonstrate that


DandErase rivals leading anti- dandruff shampoos, achieving up to a 95% reduction in dandruff within 3 days for all participants.


By rebalancing the scalp


microbiome, it effectively soothes itching and inflammation while preventing rebound effects. Notably, its benefits last


beyond the treatment, with dandruff continuing to reduce even two weeks after stopping treatment. R&D director Romain Reynaud


said: “DandErase is a 100% natural origin, low-carbon botanical active developed as part of our circular beauty strategy”.


www.personalcaremagazine.com


Elementis to unveil actives in Amsterdam


British personal care ingredient maker Elementis will debut antiperspirant actives and mineral- based rheology modifiers at the in-cosmetics Global trade show in Amsterdam, the Netherlands on 8-10 April at stand 1C30. New for 2025 is Deoluxe


SC, a novel, antiperspirant and deodorant active that addresses a key challenge in non-metal based high-performance sweat control, featuring strong and clinically proven sweat reduction. Elementis will also introduce


REACH AZP 908 LC, an aluminium active for antiperspirant products using high-quality upcycled aluminium, reducing the carbon footprint and enhancing sustainability profiles. Also on show will be the


Bentone Ultimate series including Bentone Ultimate USD and Bentone Ultimate LC that feature innovative, patent-pending oil phase rheology technology. Utilising industry leading


organically modified hectorite clay and a 100% natural activation system, this new gel technology achieves exceptionally high activity levels that supersede traditional systems. “Elementis is reshaping


the beauty and personal care industry through innovations and sustainability,” it said.


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