MARINE INGREDIENTS 65
Skin hydration improvement after 2h, 24h and 14 days 2h ■ 24h ■ 14 days ■
60.00 TEWL improvement after 24h and 14 days 24h ■ 14 days ■ 30.00 22.50 15.00 37.50 7.50 0.00 15.00 Placebo HA 0.1% Red Algae 0.025%
Figure 1: Skin hydration studies. Increases AQP3 content by 138% in vitro; +58% hydration boost after 24h in vivo
Discussion The combined dataset supports a cohesive multi- mechanistic narrative. Firstly, marine glycans provide immediate water binding and a flexible film that increases hydration quickly—this is captured by the strong two-hour uplift. Secondly, biomarker-level support of AQP3
provides a plausible biological bridge to better internal distribution and handling of water and glycerol, aligning with sustained hydration and barrier support. Thirdly, ProCollagen I stimulation provides a mechanistic anchor for dermal resilience and aligns with the firmness improvement observed at day 14.
Benchmarking Hyaluronic acid is a recognized hydration ingredient. In this dataset, Sarcothalia C at 0.025% outperformed 0.1% hyaluronic acid for hydration at two hours and 24 hours and showed greater relative barrier support at day 14. This suggests that the marine glycan profile
-7.50 Placebo HA 0.1% Red Algae 0.025%
Figure 2: Skin barrier support, x7 greater TEWL improvement than hyaluronic acid in vivo
delivers a strong film and water structuring effect and that the multi-pathway approach can outperform singlepath hydration at low HA levels.
From science to sensoria In body care, perceived dryness and roughness are tightly linked to surface water content and barrier integrity. By improving hydration and TEWL, Sarcothalia C can be positioned for immediate comfort (less tightness), smoother feel (reduced roughness), and longer-term resilience (better moisture retention). The firmness outcome adds a premium cue that is particularly relevant for mature or dry body skin.
Practical formulation guidance and claims Recommended use level The in vivo dataset validates 0.025% Sarcothalia C for body care performance. Depending on the desired sensorial profile, formulators can pair the
Skin Firmness improvement after 14 days 20.00
active with classic emollients and barrier lipids to enhance comfort while maintaining the science narrative. Formulation pairing suggestions (conceptual) ■ Pair with emollients (esters, triglycerides) for slip and reduced roughness. ■ Pair with barrier lipids (ceramides, cholesterol, fatty acids) for a stronger barrier story ■ Pair with humectants (glycerol, betaine) when an extra ‘water reservoir’ is desired ■ Use in body lotion, body cream, hand cream, aftersun care, and targeted smoothing products.
Consumer friendly claim set (aligned to measured endpoints) ■ Hydrates fast and lasts: significant hydration improvement at two hours and 24 hours ■ Helps skin retain moisture: reduced TEWL and improved barrier function ■ Supports a firmer look: measurable firmness improvement after 14 days. ■ Activates the hydration circuit: supports AQP3, the skin’s water and glycerol channel (in vitro biomarker)
10.00
Conclusion Sarcothalia C (Sarcothalia circumcincta extract) demonstrates a compelling ‘hydration matrix’ profile: fast water binding and film formation supports immediate moisturisation, while in vitro increases in AQP3 (138% of control) and ProCollagen I (124% of control) provide mechanistic anchors for intrinsic hydration handling and dermal resilience. In vivo, 0.025% Sarcothalia C delivers rapid
and durable hydration, significant barrier support via reduced TEWL, and measurable firmness improvement within 14 days — benchmarking positively versus placebo and 0.1% hyaluronic acid.
0.00 Placebo HA 0.1% Red Algae 0.025%
Figure 3: Skin firmness improvement, +124% in vitro boost in pro-Collagen I; +18% increase in firmness in vivo
www.personalcaremagazine.com This combined profile makes Sarcothalia C a
strong candidate for bodycare formulas that aim to hydrate quickly, help the skin retain moisture more effectively, and support a firmer, smoother appearance.
PCM April 2026 PERSONAL CARE MAGAZINE
% Change in 1/R0 vs initial conditions
% Increase in skin hydration compared to initial conditions and to untreated
Change in TEWL compared to initial conditions in %
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