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74 SCALP CARE


consumer demands for both performance and environmental responsibility.


The relevance of proven effectiveness In the current cosmetics landscape, consumers are increasingly informed and discerning, seeking products that deliver tangible results. This heightened demand for efficacy has driven the importance of scientifically substantiated claims in product development and marketing. Clinical studies have demonstrated the


effectiveness of novel scalp care actives in improving hair health. For example, formulations incorporating natural ingredients such as improved exosomes, plant-derived polysaccharides or microalgae extracts have shown promising results. These components, obtained through biotechnological processes, contribute to enhanced hair strength and vitality. Furthermore, plant-derived active ingredients


are finding more potential in hair care products, targeting concerns like hair fall treatment and regulation of the sebum. These innovations underscore the potential of biotechnology in developing effective scalp care solutions. An example of such innovation is SCH


ShellCare® Scalp, an encapsulated cosmetic active by Special Chemicals that combines plant-derived actives with advanced peptides. This multifunctional ingredient targets multiple therapeutic aspects of scalp health, demonstrating a 44.83% reduction in hair loss and a 27.31% increase in hair density in clinical studies over 150 days. Additionally, it has been shown to reduce


IL-6 levels by 27%, TNF-α by 36%, and enhance antioxidant potential by 33%, making it a comprehensive solution for scalp care.


Formulation potential Integrating advanced scalp actives into cosmetic formulations requires careful consideration of delivery mechanisms to ensure stability and efficacy. Encapsulation technology has emerged as a pivotal strategy in this context. Encapsulation involves enclosing active ingredients within a protective shell, such as liposomes or polymeric walls, to isolate them from environmental factors and control their release upon application. This technique offers several benefits, as follows. ■ Enhanced stability: Encapsulation protects sensitive actives from degradation caused by light, air, or other environmental factors, preserving their potency over time. ■ Controlled release: The encapsulated actives can be engineered to release gradually, ensuring a sustained effect and reducing the need for frequent application. ■ Improved formulation aesthetics: Encapsulation can convert liquid or oil-based actives into powder or bead forms, enhancing the texture and sensory properties of the final product. By employing encapsulation and other


advanced formulation techniques, cosmetic scientists can effectively incorporate potent scalp care actives into products, delivering targeted benefits while maintaining product stability and consumer appeal.


PERSONAL CARE October 2025


A new era in hair care Maintaining optimal scalp health is fundamental to achieving strong, vibrant hair. A well-nourished scalp provides the necessary foundation for robust hair growth, while imbalances can lead to dryness, dandruff, and hair loss. Recognizing these challenges, the cosmetics industry has increasingly embraced targeted solutions to address specific scalp concerns, reflecting a broader trend toward personalized and effective treatments. Innovations in scalp care—from microbiome-


friendly formulations to the incorporation of potent antioxidants—are transforming traditional hair care. These advances, underpinned by rigorous scientific research and clinical validation, not only enhance product efficacy but also build consumer trust in an era where evidence-based claims are paramount. Moreover, the industry’s move toward


sustainable and technology-driven formulations, including methods like encapsulation and green extraction processes, is setting new standards in product development. As consumer awareness continues to


grow, the demand for products that deliver measurable results will undoubtedly shape the future of the cosmetics industry. The integration of cutting-edge biotechnology and sustainable practices promises to drive further innovation, ensuring that tomorrow’s hair care solutions effectively address evolving scalp concerns while promoting overall hair vitality.


References 1. Medical News Today. Everything you need to know about DHT. 12 January 2024. https:// www.medicalnewstoday.com/articles/68082


2. Sadgrove N, Batra S, Barreto D, Rapaport J. An Updated Etiology of Hair Loss and the New Cosmeceutical Paradigm in Therapy: Clearing “the Big Eight Strikes.” Cosmetics. 2023; 10(4)


3. Malkud S. Telogen Effluvium: A Review. J Clin Diagn Res. 2015;9(9) Https://www.ncbi.nlm.nih. gov/pmc/articles/PMC4606321/


4. Cho YH, Lee SY, Jeong DW, Choi EJ, Kim YJ, Lee JG et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo- controlled trial. Evid Based Complement Alternat Med. 2014;2014:549721


5. Szendzielorz E, Spiewak R. Caffeine as an Active Molecule in Cosmetic Products for Hair


Loss: Its Mechanisms of Action in the Context of Hair Physiology and Pathology. Molecules. 2025 Jan 4;30(1):167


6. Huh S, Lee J, Jung E, Kim SC, Kang JI, Lee J et al. A cell-based system for screening hair growth-promoting agents. Arch Dermatol Res. 2009 Jun;301(5):381-5


7. Sharifi-Rad J, Quispe C, Castillo CMS, Caroca R, Lazo-Vélez MA, Antonyak H et al. Ellagic Acid: A Review on Its Natural Sources, Chemical Stability, and Therapeutic Potential. Chen L, editor. Oxid Med Cell Longev. 2022; Feb 21:2022:3848084


8. Aggarwal B, Deb L, Prasad S. Curcumin Differs from Tetrahydrocurcumin for Molecular Targets, Signaling Pathways and Cellular Responses. Molecules. 2014 Dec 24;20(1):185–205


9. Leake A, Chisholm GD, Habib FK. The effect of zinc on the 5α-reduction of testosterone by the hyperplastic human prostate gland. Journal of Steroid Biochemistry. 1984 Feb 1;20(2):651–5


10. Patel DP, Swink SM, Castelo-Soccio L. A Review of the Use of Biotin for Hair Loss. Skin Appendage Disorders. 2017;3(3):166–9


11. Rahim A, Hafiz, Amin H, Pankaj Ranjan Karn, Meghani N, Saraswathy Nagendran. Hyaluronic acid: comprehensive review of a multifunctional biopolymer. Future Journal of Pharmaceutical Sciences. 2024 Apr 24;10(1)


PC


12. Spada F, Barnes TM, Greive KA. Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems. Clinical, Cosmetic and Investigational Dermatology. 2018 Oct;Volume 11:491–7


13. Theodorou IM, Kapoukranidou D, Theodorou M, Tsetis JK, Alexandra Eleftheria Menni, Georgios Tzikos et al. Cosmeceuticals: A Review of Clinical Studies Claiming to Contain Specific, Well-Characterized Strains of Probiotics or Postbiotics. Nutrients. 2024 Aug 2;16(15):2526–6


14. Habeebuddin M, Karnati RK, Shiroorkar PN, Nagaraja S, Asdaq SMB, Khalid Anwer Md et al. Topical Probiotics: More Than a Skin Deep. Pharmaceutics. 2022 Mar 3;14(3):557


15. Oluwatobi Victoria Obayomi, Abiola Folakemi Olaniran, Stephen Olugbemiga Owa. Unveiling the role of functional foods with emphasis on prebiotics and probiotics in human health: A review. Journal of Functional Foods. 2024 Aug 1;119:106337–7


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