TRENDING TECHNOLOGIES
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Figure 5: Biomimetic exosomes structure
with natural plant extracts which set them apart from other liposome systems showcasing the synergistic effects of their contents. They also feature β-sitosterol a phytochemical compound serving as a vegetal equivalent to cholesterol. It improves the absorption and bioavailability of the biomimetic exosomes, promotes skin health and helps cell targeting. Indermal’s biomimetic exosome-like
vesicles are made with a medical-based manufacturing process and a bottom-up approach. This guarantees the reproducibility, high concentration and quality consistency of the products, that is not affected by the extraction and preconcentration processes.
High encapsulation efficiency Natural exosomes can be made to encapsulate other active ingredients but it requires highly expensive techniques like electroporation that are not viable for mass production. With our medical background experience working with exosomes and other nanovehicles we are able to encapsulate active ingredients in the exosome-like system keeping our most demanding standards of high entrapment and loading efficiency. The ability to encapsulate other actives
multiplies the potential of the natural exosomes as well as the active in itself,
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creating a unique and powerful ingredient and opens the possibilities of infinite combinations.
Surface loaded proteins Part of the proteins and peptides contained in the exosome-like formulations are located on the surface as in nature exosomes, being able to effectively execute their actions. This can be tested with the Z-potential
of the vesicle. The change in the surface Z-potential with or without the added proteins proves that some of them are located on the membrane of the vesicle.
The unique properties of avocado- derived biomimetic exosomes While exosome technology is gaining traction, not all exosomes are created equal. The choice of avocado-derived exosomes in EXO DDS Bakuchiol distinguishes this formulation from others available in the market. Avocado is a powerhouse of bioactive compounds, including essential fatty acids, vitamins, and antioxidants, which contribute to skin nourishment and protection. Its nourishing properties hydrate, protect,
and rejuvenate the skin, offering anti-ageing benefits and reducing inflammation. Known for promoting collagen production and improving
skin elasticity, it is a key addition to cosmetic formulations aimed at enhancing skin health and vitality.
Avocado: a natural boost for hydrated, healthy skin Hydration and nourishment: Avocado is packed with monounsaturated fatty acids, primarily oleic acid, which deeply nourish and moisturize the skin. This makes it an excellent choice for products targeting dry or dehydrated skin.
Antioxidant power The fruit is rich in vitamin E, vitamin C, and polyphenols, which protect the skin against oxidative stress caused by environmental aggressors such as UV rays and pollution. These antioxidants help to prevent premature ageing, giving the skin a youthful glow.
Soothing and calming The phytosterols present in avocado reduce redness and inflammation, making it suitable for sensitive or irritated skin. It promotes a calm, balanced complexion while supporting the skin’s natural healing processes.
Enhancing elasticity With its high content of vitamin A and potassium, avocado supports skin regeneration
October 2025 PERSONAL CARE
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