44 TRENDING TECHNOLOGIES
and collagen production, improving elasticity and reducing the appearance of fine lines and wrinkles.
Natural barrier support Avocado oil’s lipid profile strengthens the skin barrier, locking in moisture and protecting against external irritants. This property is particularly valuable in products for damaged or stressed skin.
Bakuchiol encapsulated in biomimetic exosome-like avocado in the ever-evolving world of skin care, where new trends and ingredients continuously emerge, Bakuchiol has recently captured the spotlight. Often referred to as a natural alternative to retinol, Bakuchiol has become a favourite among beauty enthusiasts, dermatologists, and skin care brands alike. Bakuchiol is a plant-derived compound,
extracted from the seeds and leaves of the Psoralea corylifolia plant, traditionally used in Ayurvedic and Chinese medicine for its therapeutic properties. Its ability to stimulate collagen production, improve skin texture, and reduce signs of ageing has made it a rising star in the clean beauty movement, where consumers are increasingly turning to gentler, more sustainable alternatives. The surge in Bakuchiol’s popularity can be seen as part of a broader trend in the skin care industry, where there’s a growing demand for products that provide effective results without compromising skin health or contributing to environmental harm. This demand for ‘clean beauty’ aligns with
the rise of natural ingredients and plant-based formulations, which are not only gentler on the skin but also align with consumers’ ethical and environmental values. As people become more conscious about what they apply to their skin, Bakuchiol offers a safer, sustainable alternative to synthetic retinol, making it appealing to a wide range of users, including
2.0 1.5 1.0 0.5 0.0
Figure 6: EXO DDS Bakuchiol compared to free active. In this assay, green fluorescence intensity was used as an indicator of oxidative damage. Lower fluorescence corresponds to reduced oxidative damage
those with sensitive skin. Moreover, Bakuchiol has gained traction
in skin care routines as a part of the broader clean beauty trend, which emphasizes cruelty- free, vegan, and eco-conscious formulations. With wellness and self-care being central themes in today’s beauty culture, consumers are gravitating toward products that reflect their values, which is why Bakuchiol has taken centre stage alongside other trending ingredients like hyaluronic acid, niacinamide, and peptides. These ingredients, often known for their
hydrating, soothing, and age-defying benefits, have reshaped skin care practices and continue to dominate beauty shelves globally. When bakuchiol is encapsulated in
avocado exosomes, the exosomes act as a delivery system, enhancing bakuchiol’s penetration into the skin. The avocado exosomes’ regenerative properties, rich in proteins and lipids, promote cell
-149%
2.0 1.5 1.0 0.5 0.0
communication and skin repair. This combination allows bakuchiol to work
more effectively, soothing, reducing fine lines, and improving skin texture, while benefiting from the exosome’s targeted delivery. This synergy ensures deeper nourishment, improved absorption, and better overall skin rejuvenation. The key advantages of bakuchiol are as
follows. ■ Stimulation of collagen production, reducing fine lines and wrinkles. ■ Potent antioxidant properties, protecting against oxidative stress. ■ Anti-inflammatory effects, helping to soothe sensitive or acne-prone skin. ■ Non-irritating and suitable for all skin types, including sensitive and reactive skin. ■ Photostability, meaning that bakuchiol does not break down under UV exposure, making it safer for daytime use. ■ Improvement in skin texture by promoting
-177%
Figure 7: Matrix Metalloproteinase 1 secretion at 72 hours of healthy, aged group or irradiated and treated with either EXO DDS-Ø, EXO DDS Bakuchiol, and Free Bakuchiol
PERSONAL CARE October 2025
Figure 8: IL-6 secretion at 72 hours of non-treated control hOSEC (Healthy), solar irradiation (Aged) or irradiated and treated with either EXO DDS Bakuchiol, and Free Bakuchio
www.personalcaremagazine.com
MMP-1 (Concentration in pg-ml)
IL-6 (Concentration in pg-ml)
Healthy control Treated control
EXO DDS Bakuchiol
Free Bakuchiol
Healthy control Treated control
EXO DDS Bakuchiol
Free Bakuchiol
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