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TRENDING TECHNOLOGIES


Biomimetic avocado- derived exosomes


Miriam Valdés – Nanovex Biotechnologies


In the ever-evolving world of dermatological innovation, one of the most promising advances is the use of exosome-based delivery systems for active ingredients. Among these, EXO DDS Bakuchiol, a biomimetic avocado-derived exosome encapsulating bakuchiol, represents a groundbreaking approach to anti-ageing skin care.


This unique formulation enhances the


stability, bioavailability, and efficacy of bakuchiol, multiplying its well-known skin benefits. In this article, we explore the science behind encapsulation, the role of exosomes in dermatology, and the exceptional properties of avocado-derived exosomes in comparison to conventional delivery systems.


The science of encapsulation Encapsulation technologies have become fundamental in optimizing the delivery of bioactive compounds in skin care. By encapsulating an active ingredient within a protective carrier, stability is improved, targeted delivery is enhanced, and skin penetration is optimized. This is particularly crucial for plant- derived compounds such as bakuchiol, which can degrade under certain environmental conditions. The encapsulation of bakuchiol in avocado-


derived exosomes offers several advantages, as follows. ■ Increase penetration efficacy: Up to 20 times higher compared with the free active ■ Increased stability: Exosomes provide a natural protective barrier that prevents premature degradation. ■ Enhanced bioavailability: The encapsulation allows for deeper penetration into the skin layers. ■ Controlled release: The gradual release ensures prolonged activity, reducing the risk of irritation. ■ Improved efficacy: Encapsulation can help maintain the potency of bakuchiol, ensuring better results over time. ■ Enhanced skin compatibility: By mimicking natural cellular processes, exosomal encapsulation allows for better integration with skin cells, minimizing potential adverse reactions.


DDS encapsulation system The active ingredients encapsulated in the deep delivery system are delivered specifically in the deepest layer of the epidermis for a more intense and precise effect on the structures and cells located there.


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The encapsulated active ingredients


penetrate the skin quickly and safely, without undergoing changes in their molecular structure and thereby retaining their functionality at the point of delivery increasing the penetration efficacy up to 20 times higher. Greater amount of 100% functionally active


ingredient in the specific location ensures exponentially improved results from the cosmetic formulations and increases your customer satisfaction too.


The role of biomimetic exosomes in cosmetic science The field of cosmetic science has witnessed a pioneering innovation with the introduction of biomimetic exosomes. These advanced cellular communication vehicles are revolutionizing skin care by harnessing the power of nature to enhance the effectiveness of cosmetic formulations.


Figure 1: Fluorescent vegan DDS liposomes with rhodamine-labelled phospholipids


October 2025 PERSONAL CARE


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