12 NEWS
Unilever uncovers ageing link with skin microbiome
Unilever research has uncovered evidence that the bacteria living on our skin – known as the skin microbiome – may influence premature ageing based on facial appearance. A first-of-a-kind study, published in the British Journal of Dermatology, compared individuals of the same chronological age but with visibly different ageing profiles. Skin microbiome as a signature
of premature ageing appearance: Manipulation through use of topical products found that individuals with ‘delayed ageing’ had a more resilient and stable microbial community on their skin, with an abundance of a bacteria called Acinetobacter. In contrast, those with premature
ageing showed a more fragile microbiome structure. “This is the first study to
compare the skin microbiome of people with different visible ageing profiles but the same chronological age — suggesting the skin microbiome could be a contributor in how we look,” said a Unilever spokeswoman. The research also revealed
Valencia show to discuss skin longevity
The 16th International Congress on Skin Ageing & Challenges in Valencia, Spain this November will discuss new strategies for skin longevity.
The meeting on 11-12
November will address the biological complexity of skin ageing, which is shaped by both intrinsic factors (cellular senescence, genetic programming, protein homeostasis) and extrinsic factors (UV exposure, pollution, microbiome shifts). The congress will bring
that applying a topical skin care product containing the ingredient retinyl propionate - a retinoid used in some anti-ageing and skin- renewing skin care products - not only improved age-related skin physiology but also shifted the microbiome to resemble that of younger-looking individuals. Thirty volunteers with
premature ageing appearance used a marketed facial cleanser (0.6 g) followed by a marketed cream
(0.6 g) with retinyl propionate twice daily for four weeks. In addition to the effect on skin
microbiome, product intervention led to improved ageing skin features of wrinkle, pore, hydration, barrier, elasticity, and brightness. “This suggests that skin care
can influence the skin’s microbial network — potentially opening the door to microbiome-targeted anti-ageing solutions in the future,” added the spokeswoman.
Keratin from wool found to repair teeth
British researchers have discovered that keratin, a protein found in hair, skin and wool, can repair tooth enamel and stop early stages of decay.
The King’s College London
(KCL) team of scientists discovered that keratin produces a protective coating that mimics the structure and function of natural enamel when it comes into contact with minerals in saliva. In their study, published in
Advanced Healthcare Materials, the scientists extracted keratin from wool. They discovered that when
keratin is applied to the tooth surface and comes into contact with the minerals naturally present in saliva, it forms a highly organised, crystal-like scaffold that mimics the structure and function of natural enamel. Over time, this scaffold
continues to attract calcium and phosphate ions, leading to the
PERSONAL CARE October 2025
growth of a protective enamel-like coating around the tooth. This marks a significant step
forward in regenerative dentistry, says KCL. “Keratin offers a transformative
alternative to current dental treatments. Not only is it sustainably sourced from biological waste materials like hair and skin,
but it also eliminates the need for traditional plastic resins, commonly used in restorative dentistry, which are toxic and less durable,” said KCL researcher and study first author Sara Gamea, PhD. “Keratin also looks much more
natural than these treatments, as it can more closely match the colour of the original tooth.” As concerns grow over the
sustainability of healthcare materials and long-term fluoride use, this discovery positions keratin as a leading candidate for future dental care. The research also aligns with
broader efforts to embrace circular, waste-to-health innovations, transforming what would otherwise be discarded into a valuable clinical resource.
Gamea added: “This technology
bridges the gap between biology and dentistry, providing an eco- friendly biomaterial that mirrors natural processes.”
together a global panel of scientists, clinicians, and industry innovators to explore the latest breakthroughs in skin ageing research, from molecular mechanisms to real-world applications in prevention, rejuvenation, and smart skin care. The congress will open
with a keynote by Professor Vladimir A. Botchkarev of Boston University School of Medicine, USA on the epigenetic regulation of skin ageing- associated genes in short-lived and long-lived mammals — a comparative approach that could identify novel protective pathways. Key themes across the
two-day event include Cellular Senescence & Interventions; Epigenetic & Circadian Control; Skin-Microbiome-Immune Dialogue; Damage, Repair & Proteostasis; and From Lab to Market. Researchers and companies
are invited to submit abstracts for short oral presentations and innovation pitches. Dedicated sessions
will spotlight polyphenol innovations, smart biomaterials, and other emerging technologies ready for clinical and commercial translation. “The skin is both a barrier
and a biological sensor,” said Jean Krutmann, President of Skin Ageing & Challenges 2025. “By understanding its ageing
processes, we not only improve dermatological health but also gain insights into systemic ageing and potential whole- body rejuvenation strategies.”
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