255. liquid–liquid extraction Sample extraction that relies on the partitioning of an analyte between an aqueous component and a water-immiscible organic component.
256. locked nucleic acid (LNA) Oligonucleotide containing one or more of the 2´-O,4´-C- methylene-β-D-ribofuranosyl nucleosides called LNA monomers. The major feature of LNAs is the high-affinity hybridization to complementary nucleic acids because of high thermo-stability, resulting in enhanced selectivity and assay sensitivity.
257. long-term stability Assessment of the degradation of an analyte in the matrix compared with the starting, freshly prepared material following extended periods of frozen storage.
258. lower limit of quantification (LLOQ) The lowest amount of analyte in a sample that can be quantitatively determined with predefined precision and accuracy.