Definitions 315. nuclear magnetic resonance (NMR)


spectroscopy Analytical technique that exploits the magnetic properties of some atomic nuclei to determine the physical and chemical properties of the atoms or molecules that contain them. Can provide highly detailed structural information and can be used both quantitatively and qualitatively.


316. oligonucleotide A strand of DNA or RNA, typically less than 30 nucleotide units.


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317. online extraction A bioanalytical methodology that integrates sample extraction, typically in the solid-phase extraction format, and chromatography after injecting biological samples such as plasma with minimal pre-treatment.


318. optimization The process of varying the conditions of an analytical method to determine the optimal method conditions. It should be evaluated utilizing a Design of Experiments methodology.


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