The Bioanalysis Glossary


198. IC50 Measure of the potency of an inhibitor on its biological target,


measured as the concentration of inhibitor required to reduce the target’s binding ability or function by 50%, which is dependent on the concentration of the target.


199. immobilization capacity Maximum amount of ligand that can be immobilized on the surface of one plate well or beads.


200. immunoaffinity-LC–MS/MS (IA-MS) Using a capture protein, aptamer or antibody to extract target analytes from a biological sample matrix prior to LC–MS analysis.


Sponsored by


201. immunoaffinity chromatography Type of liquid chromatography in which the stationary phase consists of an antibody or antibody-related reagent. The method can be used in assays for a particular target or for purification and concentration of analytes prior to further examination by another technique.


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Bioanalysis (2020) 12(21) Suppl. 1


future science group


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