76. candidate surrogate end point An end point that is still being assessed for its ability to predict clinical benefit.
77. capacity factor Also known as ‘retention factor’, k (previously k´) applies to isocratic column chromatography. A measure of chromatographic retention, for which the calculation involves both the retention time and the column void time. k = (tr time and t0
-t0 is the dead time.
78. capillary zone electrophoresis Method in which analytes are separated in liquid media or in a gel matrix in a narrow-bore capillary, based on differential migration due to their charge-to-size ratio. Separation is performed in a narrow-bore capillary generally filled with a buffer solution across which an electric potential is applied.
79. capture capability Ability of the immobilized ligand on the surface of a plate well, bead or another surface to capture the target from the sample solution.