29. aptamer Nucleic acid molecule engineered to bind to various molecular targets. The mode of action of an aptamer is dependent upon its shape but not its sequence.
30. aqueous normal-phase liquid chromatography
(ANP-LC) A variant of normal-phase liquid chromatography (in which the stationary phase is more polar than the mobile phase) for which the mobile phase components and additives are water-miscible. Hydrophilic interaction liquid chromatography (HILIC) and chromatography on silica hydride-based phases are popular examples of ANP-LC.
31. archive Collection and storage of records (e.g., raw data, protocols and reports) and specimens for a defined period of time. Typically as part of regulatory compliance and requiring security, and has limited access.
32. area under the curve (AUC) The area under the plot of matrix (e.g., plasma) concentration of drug against time after drug administration, linked to bioavailability measurement.
