Definitions


48. bias The difference between an experimental value and a nominal value expressed as a percentage, sometimes used as a measure of accuracy or trueness.


Bias (%) = [(Experimental value - Nominal Value)/Nominal Value] × 100%.


49. bioanalysis The quantitative or qualitative measurement of endogenous or exogenous analytes in biological matrices, including tissue, blood, serum, urine or other body fluids.


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50. bioassay Analysis of the potency or strength of a substance (such as a drug) by comparing its effects on living cells or tissue in vitro, or living animals in vivo, with its effects on a standard preparation.


51. bioavailability The fraction of a drug dose that reaches the systemic circulation unchanged, also indicated by the area under the curve in a pharmacokinetic plot post-administration of a drug.


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