Definitions


377. principal investigator An individual who acts on behalf of the Study Director and has defined responsibility for delegated phases of the study. The Study Director’s responsibility for the overall conduct of the study cannot be delegated to the Principal Investigator(s).


378. processed sample The final extract (prior to instrumental analysis) of a sample that has been subjected to various manipulations (e.g., extraction, dilution, concentration).


379. processing batch A group of unknown samples from study subjects, calibrators and a set of QCs that are subjected to the analytical methodology together.


380. prodrug A substance designed to be converted to its active form in the body after administration. A prodrug is typically synthesized to enhance the systemic absorption of the active drug.


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