91. clinical benefit A clinically meaningful, positive effect of an intervention; for example, the reduction of pain, increased sense of well-being, a positive effect on how an individual functions or survives. Usually related to a bioanalytically determined drug concentration such as a steady state or trough value measured during the trial.
92. clinical bioanalytical sample A sample received from a patient or healthy volunteer (e.g., from a clinical trial) for bioanalysis.
93. clinical laboratory improvement
amendments (CLIA) Regulates clinical laboratory diagnostic testing in the USA and requires clinical laboratories to be certificated.
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94. clinical outcome An outcome that defines or portrays how an individual feels, functions or survives.
95. clinical trial Study to evaluate a new drug or treatment in healthy or diseased human subjects.
