The Bioanalysis Glossary


24. antibody–drug conjugate (ADC) Biologically active small molecule (payload) chemically linked to a monoclonal antibody (mAb).


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25. anticoagulant A substance added to the blood during sample collection to prevent blood clotting (coagulation).


26. antidrug antibody (ADA) Also known as ‘antitherapeutic antibody’, a pre-existing or treatment-induced antibody that is capable of binding to the drug. In addition to proteins, opiates, sulfa drugs and other small molecules that can induce ADAs.


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27. antigen A substance eliciting the formation of antibodies in a suitable host.


28. antisense oligonucleotide A short nucleotide polymer that can bond to mRNA and block the process of gene expression.


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Bioanalysis (2020) 12(21) Suppl. 1


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