20. analytical run A complete set of analytical and study samples including an appropriate number of standards and quality control samples (QCs).
21. anchor calibrator Standard point outside of the range of quantification used to assist in fitting the nonlinear regression (e.g., 4-parameter or 5-parameter logistic) of the standard (calibration) curve in ligand-binding assays (LBAs).
22. anti-idiotypic antibody Antibody that binds to the idiotope of another antibody; the variable part of an antibody including the unique antigen-binding site is known as the idiotype; the idiotopes are the combination of epitopes within the idiotype, and are unique for each antibody. Anti-idiotypic antibodies can be generated to bind specifically to one monoclonal antibody drug.
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23. antibody A protein molecule generated in vivo in response to treatment with an antigen that is capable of binding to a specific determinant on the antigen. Also used as biotherapeutics.
