362. polymerase chain reaction (PCR) A molecular biological method used to enzymatically amplify a single or few copies of a particular DNA sequence using short DNA sequences called DNA primers.
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363. population-specific cut point A threshold level determined for and applied to a target population to define the presence or absence of a response.
364. post-column infusion Technique for the evaluation of matrix effect profiles in LC–MS analysis, by injection of a solvent blank or matrix blank into the chromatography column while simultaneously infusing analyte by a syringe pump to the column effluent before the detection device.
365. post-translational modification (PTM) Chemical modification to poly peptides, such as the attachment of functional groups (phosphate, carbohydrates) during their biosynthesis but after their translation from the mRNA sequence.