328. parallelism A condition in which dilution of test samples does not result in biased measurements of the analyte concentration. Determined for immunoassays by comparison of the responses from the calibration standard curve and serially diluted study samples in order to detect possible matrix effect or differing affinities for metabolites.
329. paratope The part of an antibody that recognizes an antigen.
330. partial least-squares regression (PLS) Well-established regression-based method thanks to its ability to deal with many correlated variables or in situations where fewer observations than measured variables are available. PLS builds a low-dimensional subspace by maximizing the covariance between the data and the class assignment. Orthogonal partial least squares analysis (O-PLS) and O2-PLS are recent extensions of the PLS method applied to many fields, such as for metabolomic data.