133. dried blood spot (DBS) sampling A matrix-sampling methodology based on applying whole blood (e.g., obtained from venous draws or a heel-, tail- or finger-prick) onto a (paper) substrate, which is subsequently dried and sealed in bags with desiccant for possible storage and shipping prior to extraction and analysis.
134. drug metabolism See ‘Biotransformation’.
135. drug–drug interaction The effect of co-administered drugs on the pharmacokinetics (PK) and pharmacodynamics (PD) of the drug of interest. This often results from competitive binding at one enzyme, transporter, or receptor.
Sponsored by
136. dry-down The evaporation of solvents, typically organic, from sample extracts during the sample preparation process.
