462. system priming Injection of extracted biological samples into an HPLC system prior to the run under the chromatographic condition for the analytical run. System priming is mainly for blocking active sites that may adversely adsorb the analytes of interest. It should not be confused with system suitability.
463. system suitability Determination of instrument performance (e.g., sensitivity, chromatographic retention and resolution) by analysis of specific samples conducted prior to submission of the analytical run.
464. tandem mass spectrometry Mass spectrometry employing two analytical stages, typically separated in space (e.g., triple quadrupole or quadrupole-time of flight) or separated in time (e.g., 3D ion trap).
