TESTING
revolutionised biological understanding and streamlined product development. Its short lifespan, human gene homology, well-defined anatomy, and ease of cultivation makes it a popular assay choice to investigate the toxicity of new bioactive molecules or microbial pathogenicity in a whole organism. By facilitating the rapid elimination of
early-stage risks, C. elegans saves companies significant time and resources. This translates to increased confidence moving into clinical trials, as researchers gain a deeper understanding of a probiotic's mechanisms and expected benefits on the body and other organs including the skin.
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2. Hill C, Guarner F, Reid G, Gibson GR, Merenstein DJ, Pot B et al. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term Probiotic. Nature Reviews Gastroenterology & Hepatology. 2014; Jun 10;11(8):506–14
3. Understanding the health benefits of taking probiotics [Internet]. Harvard Medical School; 2022.
https://www.health.harvard. edu/nutrition/understanding-the-health- benefits-of-taking-probiotics
4. Gao T, Wang X, Li Y, Ren F. The role of
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PC Old Worm - leaky gut
probiotics in skin health and related gut– skin axis: A Review. Nutrients. 2023 Jul 13;15(14):3123
5. Álvarez-Arraño V, Martín-Peláez S. Effects of probiotics and synbiotics on weight loss in subjects with overweight or obesity: A systematic review. Nutrients. 2021; Oct 17;13(10):3627
6. Bodke H, Jogdand S. Role of probiotics in human health. Cureus. 2022; Nov 9
7. European Commission. Ban on animal testing.
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8. Qi Y, Yu L, Tian F, Zhao J, Zhai Q. In vitro models to study human gut-microbiota interactions: Applications, advances, and limitations. Microbiological Research. 2023; May; 270:127336
Old Worm - leaky gut
9. Labarre A, Guitard E, Tossing G, Forest A, Bareke E, Labrecque M, et al. Fatty acids derived from the probiotic Lacticaseibacillus rhamnosus HA-114 suppress age-dependent neurodegeneration. Communications Biology. 2022 Dec 7;5(1). doi:10.1038/ s42003-022-04295-8
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November 2024 PERSONAL CARE
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