78 SKIN CARE As shown in Figure 2, after 42 days of


treatment, 0.00025% of enriched OBG significantly reduced the telomere shortening rate, compared to the control. This suggests that enriched OBG exerts beneficial effects by decreasing telomere shortening rate and preserving telomere length, which supports cellular longevity. The assessment of cells with short


telomeres involved measuring the percentage of cells with specific average telomere length, which reflected the telomeric profile at the cellular level. This metric accounts for the effects of senescence and apoptosis. A higher percentage of cells with shorter telomeres indicates closer proximity to senescence. As shown in Figure 3, the control displays


a telomere length peak at 10,500 bp, whereas the cells treated with 0.00025% enriched OBG exhibited a peak at 11,500 bp. After 42 days of treatment, enriched OBG results in a lower percentage of cells with short telomeres and a higher percentage of cells with longer telomeres, compared to the control. These findings suggest that enriched OBG helps delay ageing by preventing telomere shortening.


Counteracting flaky and dry desquamation with enriched oat beta-glucan Desquamation, the process of shedding dead skin cells, is essential for epidermal renewal and the removal of damaged or non-functional corneocytes, helping to maintain a healthy and hydrated appearance.6 Normal desquamation is crucial for the


proper functioning of the stratum corneum and for sustaining skin appearance. However, excessive desquamation can lead to the accumulation of dead cells, disrupting the skin’s barrier and resulting in dryness and flakiness. An in vivo study was conducted to assess


the effectiveness of enriched OBG in reducing skin desquamation over 28 days compared to a placebo. The study involved 20 female participants of various ethnic backgrounds (Caucasian, Hispanic and African American), aged 33 to 66, with mixed skin types (sensitive or healthy). Participants applied enriched OBG cream


(containing Aqua, Glycerin, Disodium EDTA, Glyceryl Stearate, PEG-100 Stearate, C12-15 Alkyl Benzoate, Dimethicone, Cetearyl Alcohol, Stearyl Alcohol, Ceteareth 20, Phenoxyethanol, Ethylhexylglycerin, Avena sativa (Oat) Bran Extract) and a placebo cream (with the same ingredients minus the Avena sativa (Oat) Bran Extract) to their forearms and upper arms twice daily, morning and evening, over 28 days. Measurements were taken on day 0 (before treatment), day 7 and day 28. Skin desquamation was evaluated using the


Corneofix F20, which analyses photographs of an adhesive sheet that collects skin flakes from the surface. The device calculated the desquamation rate based on the image, where different colours correspond to the thickness and size of the corneocytes. After 28 days of application, 1% enriched


OBG treatment demonstrated cell renewal and hydrated skin, while the placebo showed


PERSONAL CARE March 2025 105 100 -8%* 95 90 85 80 Day 0 Day 28 Day 56


Figure 5: Roughness area reduction over 56 days with enriched OBG treatment. T-test, significant: ***=p<0.001, *=p<0.05 (95%)


dry and flaky skin (Figure 4). Dryness and the build-up of dead skin cells are the primary factors that lead to changes in skin texture. This suggests that enriched OBG promotes cell renewal and counteracts dry desquamation (dead cell accumulation), leading to an improvement in skin texture.


Smoothing and improving skin texture with enriched oat beta- glucan Skin smoothness and texture refer to the skin’s surface, which can be enhanced by reducing roughness, unevenness and imperfections. Achieving smoother skin often improves light reflection, contributing to a more radiant, youthful appearance. A blind in vivo study was conducted to


evaluate the anti-roughness effect of enriched OBG compared with a placebo. The study included 20 female participants


of Caucasian and Hispanic backgrounds, aged 30 to 54, with mixed skin types (dry, oily or combination). Over 56 days, participants applied enriched OBG face serum (containing Aqua, Sodium Acrylates Copolymer, Lecithin, Sodium Gluconate, Avena sativa (Oat) Bran Extract, Phenoxyethanol, Ethylhexylglycerin, Caprylic/Capric Triglyceride) to one half of their face and a placebo serum - with the same ingredients minus the Avena sativa (Oat) Bran Extract) - to the other half, with treatment areas randomised. The products were applied twice daily, in the morning and evening. Measurements were taken on day 0 (before treatment), day 28 and day 56. Skin roughness area was assessed in the cheekbone area of the face using the AEVA- HE V4 system. Skin roughness area refers to the quantitative assessment of the total irregularities in a specific area of the skin. 1% enriched OBG significantly reduced


roughness area after 28 and 56 days of treatment compared to the baseline (Figure 5). In contrast, the placebo showed no relevant effects on skin roughness. Rough skin texture can trap and scatter light, making the skin appear dull and tired. These finding validate that enriched OBG smooths the skin, enhancing skin reflectivity.


Enhancing skin brightness and evens skin tone with enriched oat beta-glucan Skin brightness results from a radiant and luminous appearance, free from dullness, allowing light to reflect evenly. An even skin tone means a uniform complexion that enhances overall brightness and creates a smooth, balanced look. A blind in vivo study was performed to


evaluate the efficacy of enriched OBG on skin radiance compared to a placebo. The study included 20 female participants of Caucasian and Hispanic backgrounds, aged 25 to 51, with mixed skin types (dry or combination) and stressful lifestyles, including lack of sleep. Over 28 days, participants applied enriched OBG face serum (containing Aqua, Phenoxyethanol, Ethylhexylglycerin, Sodium Phytate, Sodium Acrylates Copolymer, Lecithin, Caprylic/Capric Triglyceride, Avena sativa (Oat) Bran Extract) to one half of their face and a placebo serum (with the same ingredients minus the Avena sativa (Oat) Bran Extract) to the other half, with the treatment areas randomised. The face serums were applied twice daily, in the morning and evening. Measurements were taken on day 0 (before treatment), day 1 and day 28.


Diffuse brightness was performed in the cheekbone area of the face, using a Nikon D5600 installed in the HeadScan Bench Light Face and Frame Scan software for 2D image analysis.


www.personalcaremagazine.com -17%*** Placebo ■ 1% Enriched Oat Beta Glucan ■


Roughness Area Mean Values (%)


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