76 SKIN CARE
Oat beta-glucan active for enhanced cell life
Emilie Gombert – Oat Cosmetics ABSTRACT
With age, the skin’s appearance deteriorates, becoming rougher, duller and more prone to developing uneven tone. However, there are ways to delay these signs by targeting key mechanisms at the cellular level, specifically by protecting telomeres. Oat Cosmetics has developed Rejuvaveen (Avena sativa (Oat) Bran Extract), an enriched oat beta-glucan active designed to preserve telomere integrity and rejuvenate the skin. This article explores how Rejuvaveen reduces skin roughness, enhances radiance and promotes a youthful appearance.
Throughout the ageing process, skin undergoes a series of structural and functional changes that contribute to a noticeable decline in texture quality and skin radiance.1
This loss
of radiance, characterised by diminished luminosity and a more uneven complexion, is primarily due to the skin’s gradual decrease in ability to regenerate and repair itself effectively. As skin cells age, their renewal rate slows
down, causing an accumulation of dead cells on the skin’s surface. This buildup contributes
to a rougher texture and a dull, lacklustre appearance.2 Cellular ageing plays a central role in these
changes, with telomere shortening emerging as a key factor. Telomeres are repetitive DNA sequences at the ends of chromosomes, acting as protective caps that preserve genetic material during cell division.3 Each time a cell divides, its telomeres
shorten, eventually leading to cellular senescence—a state in which cells can no longer divide or function optimally. In skin
Environmental Factors (UV, pollution) Stress
Hormonal and Enzymatic Factors
Dryness Thinner skin
Stratum Corneum Epidermis
Visible Wrinkles & Fines Lines Changing Texture
Duller skin Dermis
Telomere Shortening
Figure 1: Premature ageing: visible signs of stress-induced skin ageing PERSONAL CARE March 2025
cells, including fibroblasts and keratinocytes, telomere attrition is closely associated with the ageing of dermal cells, which are essential for maintaining the skin’s structural integrity and radiance.4
Understanding telomeres and their role in skin health When telomeres shorten and cells become senescent, the production of vital proteins such as collagen and elastin diminishes, leading to a decline in skin texture, elasticity and overall smoothness. Senescent cells produce higher levels of reactive oxygen species (ROS) and pro-inflammatory cytokines, which exacerbate oxidative stress and inflammation. This inflammatory environment further disrupts the skin’s natural barrier function and accelerates the degradation of extracellular matrix components, resulting in a more uneven and rough texture.5 These changes are intricately linked to
the reduction in skin radiance. The decline in cellular function and deterioration of the extracellular matrix causes the skin’s surface to become less smooth, impairing its ability to reflect light evenly. Combined with increased oxidative stress, this leads to a dull and lacklustre appearance. Ultimately, these factors contribute to a visibly aged complexion characterised by uneven texture
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