PRESERVATIVES 31 CFU/mL*


1.00E+06 8.00E+05 6.00E+05 4.00E+05 2.00E+05 0.00E+00


Inoculum 24h 7 days 14 days


n Escherichia coil ATCC 8739 n Staphylococcus aureus ATCC 6538 n Pseudomonas aeruginosa ATCC 9027


21 days 28 days CFU/mL*


3.00E+04 2.50E+04 2.00E+04 1.50E+04 1.00E+04 5.00E+03 0.00E+00


Inoculum 24h 7 days 14 days


n Candida albicans ATCC 10231 n Aspergillus brasiliensis ATCC 16404


Figure 3: Results of PET (ISO11930) performed on an O/W emulsion with Hinoline as the sole anti-microbial at 2%.


References 1 https://www.ecoviaint.com/


2 Organic Personal Care Market Analysis by Product and Segment Forecasts to 2020, Gran View Research, 2015


3 Mitarotonda A, et al. Use of Sigesbeckia Orientalis Extract as an effective booster for natural preservative systems, SOFW 2010; 136:8


4 Mitarotonda A, et al. The use of Vanillin as a preservation booster for cosmetic systems,


23rd IFSCC Congress, Zurich, September 2015


5 Mitarotonda A, et al. From aromatherapy to cosmetics: how can cosmetic formulators benefit from essential oils? H&PC 2017; 12(6)


6 Yau Tang L, et al. The Essential Oil of Chamaecyparis Taiwanensis, Masamune et Suzuki. I, II and III. J Chin Chem Soc 1957; 4(1,2)


7 Li J et al. Hinokitiol Reduces Matrix Metalloproteinase Expression by Inhibiting Wnt/β-Catenin Signaling in Vitro and in Vivo,


Int Immunopharmacol. 2014; 23(1):85-91.


8 Cherng JY et al. Preventive Effects of β-Thujaplicin Against UVB-induced MMP-1 and MMP-3 mRNA Expressions in Skin Fibroblasts, Am J Chin Med. 2012; 40(2):387-98.


9 Baba T et al. Inhibitory Effect of Beta- Thujaplicin on Ultraviolet B-induced Apoptosis in Mouse Keratinocytes, J Invest Dermatol. 1998; 110(1):24-8


10 Mojtaba S, et al. Journal of Advanced Research. 6, 155–162, 2015


21 days 28 days


September 2020


PERSONAL CARE EUROPE


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