84 FRAGRANCES Anionic Gel with Naticide 1% Anionic Emulsion with Naticide 1% n Bacteria gram + n Bacteria gram - n Moulds n Yeasts
7 6 5 4 3 2 1 0
0 7 Days 14 28
7 6 5 4 3 2 1 0
Yeasts Moulds
Bacteria gram – Bacteria gram +
0 7 Days 14 28
Microbial survival < 0.2% : adequate Microbial survival < 1 : debatable Microbial survival <10% : insufficient Microbial survival >10% : inadequate
Figure 1: Anionic gel and emulsion with Naticide 1%.
decrease of the microbial populations (-99.9%) has been registered with no further growth after 14 and 28 days. All the formulations, as shown, have been adequately preserved with the vegetable extract blend. Only in one case, and due to a different method of manufacturing, microbial count resulted ‘debatable’ at the first count at 7 days. Besides these two cases, the product preservation resulted ‘adequate’ after 14 and 28 days to the inoculum.
Table 2 Products
Non ionic gel (naticide 0.5%) Non ionic gel (naticide 1%) Anionic gel (naticide 0.5%) Anionic gel (naticide 1%) Solution (naticide 0.5%) Solution (naticide 1%)
Hydroalcoholic solution (naticide 0.5%) Hydroalcoholic solution (naticide 1%)
Shampoo (naticide 0.5%) day 7, day 14, day 28
Shampoo (naticide 1%)
O/W emulsion (naticide 0.5%)1 O/W emulsion (naticide 1%)2 O/W emulsion (naticide 0.5%)3
Day 14,28 O/W emulsion (naticide 1%)3 1 Naticide in hydrophilic phase at 0.5% with solubiliser
2 Naticide into hydrophilic phase at 0.5% with solubiliser + 0.5% at the end of manufacturing process with solubiliser 3 Naticide at the end of manufacturing process with solubiliser
PERSONAL CARE ASIA PACIFIC Day 7
The vegetable extract blend can be thus considered a high performance growth inhibitor, with a high efficacy against all microorganisms tested.
Formulating with the vegetable extract blend
The vegetable extract blend can be used in a wide range of personal care formulations such as creams, lotions, shampoos, conditioners, etc.
It is water dispersible only up to 0.6%,
Bacteria G+/- u.f.c/g/ml
<10 <10 <10 <10 <10 <10 <10 <10
<10 <10
<10 <10 <10
300 (0.0015%) <10
<10
Moulds u.f.c/g/ml
<10 <10 <10 <10 <10 <10 <10 <10
<10 <10
<10 <10 <10
<10 <10
<10 Yeasts
u.f.c/g/ml <10 <10 <10 <10 <10 <10 <10 <10
5.000 (0.5%) <10
<10 <10 <10
1.000 (0.1%) <10
<10
which means this is the maximum amount that can be added to the hydrophilic phase. In case of higher percentage, the remaining amount is to be added at the end of the formulation. It is recommended the usage of proper solubilising agent into the hydrophilic phase.
The vegetable extract blend performs its antimicrobial activity in a pH range 4-9. Below there are some formulative guidelines using the vegetable extract blend: a soap and a cream.
Conclusion
Consumers continue to seek products that offer both small ingredients lists and include as many natural ingredients as possible. This can create tough challenges for formulators, but multifunctional ingredients such as Sinerga’s Naticide can help with both these issues. Naticide is a nature-identical ingredient,
created by Sinerga Research Centre, with a wide and complete spectrum activity, effective against Gram-positive, Gram- negative, yeasts and moulds in a pH range between 4 - 9.
Thanks to its light, sweet, vanilla-like
aroma, the use of additional perfumes can be avoided and Naticide can also provide the base for a fresh and natural scent. It is safe, easy-to-handle and extremely skin compliant, as well as possessing excellent stability and skin tolerability. It offers a new concept for safe and
preservative-free formulations of cosmetics according to the most innovative market trends. In addition, the ingredient also has fragrance fixative properties.
PC November 2017
Yeasts Moulds
Bacteria gram – Bacteria gram +
Log
Log
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