82 SYNTHETIC BIOLOGY
As science accelerates its understanding of the impact of the genetics that varies between us all, bioinformatics techniques will aid the assessment of gene variants. This will allow us to make sense of the large and complex biological datasets that come from gene-based diagnostic tests. From a personal care perspective, it will
provide valuable insights to enable better sequence conservation of skincare proteins, or identification and quantification of proteins in skin or hair. For instance, there are many ways to enhance skin protein quality but there are also many different sources; it is still unclear whether hydrolysed collagen from mammals, fish, caviar, or recombinant bacteria is best. Once this question is resolved, sustainability and quality factors will be improved by cloning the target gene into a production vector, probably yeast. Combining genetic knowledge, SynBio,
and large-scale bioinformatics presents vast opportunities to reconfigure the personal care market toward full personalisation, offering each customer exactly what they need rather than a choice of standard formulations. In this scenario, the large-scale manufacture of separate ingredients remains similar, but for true personalisation, final formulation and mixing may be moved closer to point-of-sale with immediate customer benefit.
The short, medium and long-term outlook So, what does the future hold for SynBio in personal care? In the short to medium term, we can expect a shift from the niche production of small-volume functional ingredients to greater support of the entire product. SynBio-led production of high-volume ingredients such as carriers, surfactants, and excipients would have a greater impact on overall product sustainability. Packaging is also likely to receive a SynBio
overhaul. Also in the near future, sophisticated personalisation services like those outlined above will come to fruition at a premium price, offering tantalising commercial prospects. Looking further ahead, learnings from
activity in the medical space surrounding non-proteinogenic (unnatural) amino acids are likely to filter through to personal care. The sector’s SynBio work to date has largely focused on reproducing the amino acids that make up proteins in plants and animals. However, unnatural amino acids may reveal
different ways to enhance product functionality or unlock entirely new physiological benefits. While the major material benefits that SynBio
can bring to personal care still lie some way in the future, there is much promising activity underway. For now, we can feel cautiously optimistic about the potential it brings to meet heightened consumer demand for clean, sustainable, and personalised products.
se/2022/06/06/2456434/28124/en/Global- Beauty-Personal-Care-Market-Report-2022- Market-is-Forecasted-to-reach-615-92- Billion-in-2026-Increasing-Premiumisation-
Adoption-of-Augmented-Reality.html
2. Forbes. Synthetic Biology Is Disrupting Personal Care, Making It More Sustainable — And More Personal. 10 September 2019.
https://www.forbes.com/sites/ johncumbers/2019/09/10/synthetic-biology- is-disrupting-personal-care-making-it-more- sustainable-and-personal/?sh=4126eba947c5
3. Labiotech. CRISPR Can Help The Switch To Sustainable Cosmetics. 16 May 2022. https://
www.labiotech.eu/opinion/crispr-cosmetics- ers-genomics/
4. The Economist. Could cosmetics get a makeover? 23 June 2022. https://www.
economist.com/films/2022/06/23/could- cosmetics-get-a-makeover
5. Evolva. Nootkatone.
https://evolva.com/ evenootkatone/
6. Amyris. Manool.
https://amyris.com/ ingredient/manool
7. UK Research and Innovation. Frontier Manufacturing: Scaling up synthetic biology.
https://gtr.ukri.org/ projects?ref=EP%2FK038648%2F1
8. A systematic approach to scaling up synthetic biology. Nature.
https://www.nature.com/ articles/d42473-020-00226-5
9. The Brink (Boston University). Scaling up synthetic biology. 23 January 2015. https://
www.bu.edu/articles/2015/scaling-up- synthetic-biology/
PC
References 1. Research and Markets. Global Beauty & Personal Care Market Report 2022: Market is Forecasted to reach $615.92 Billion in 2026 - Increasing Premiumisation & Adoption of Augmented Reality. 6 June 2002. https://
www.globenewswire.com/en/news-relea
PERSONAL CARE October 2023
10. Locus Performance Ingredients. https://locuspi. com/about/company/
11. c16 Biosciences. c16 Biosciences Raises $20 Million Series A to Produce Bio-Based Palm Oil Alternative for Consumer Products. 2 March 2020.
https://www.c16bio.com/c16- biosciences-raises-20-million-series-a-to- produce-bio-based-palm-oil-alternative-for- consumer-products
12. CB Therapeutics Announces Closing of the
Latest Round of Equity Funding for Scaling Up Biosynthesis Research and Production. 16 April 2019.
https://www.businesswire.com/news/ home/20190416005306/en/CB-Therapeutics- Announces-Closing-of-the-Latest-Round-of- Equity-Funding-for-Scaling-Up-Biosynthesis- Research-and-Production
13. Renewable Carbon News. Biotensidon: Breakthrough in Rhamnolipid Mass- Production. 31 January 2017. https://renewable-
carbon.eu/news/biotensidon-breakthrough- in-rhamnolipid-mass-production/
14. Geltor. HumaColl21.
https://geltor.com/ products/humacoll21/
15. Bolt Threads. b-silk.
https://boltthreads.com/ technology/silk-protein/
16. Sederma. Silverfree and Apiscalp. https://www.
crodapersonalcare.com/en-gb/our-brands/ sederma
17. Green Queen. Unilever Announces $120 Million Investment To Scale Production Of Palm Oil Alternative. 22 June 2022. https://
www.greenqueen.com.hk/unilever-invests-in- sustainable-palm-oil-alternative/
18. Biosyntia. Biosyntia and Givaudan enter long- term collaboration for sustainable ingredient development. September 2021. https://www.
biosyntia.com/biosyntia-and-givaudan-enter- long-term-collaboration
19. Proctor & Gamble. Bioresearchers of the future get £22.5million boost. 8 October 2021. https://
www.pg.co.uk/blogs/bio-researchers-of-the- future/
20. Competition and Markets Authority. Global sweep finds 40% of firms’ green claims could be misleading. 28 January 2021. https://www.
gov.uk/government/news/global-sweep- finds-40-of-firms-green-claims-could-be- misleading
21. Science Group Sustainability. Major players R&D leaders collaborate to help land Net Zero ambitions. 11 July 2022. https://www.
sagentiainnovation.com/news-detail/major- players-rd-leaders-collaborate-to-help-land- net-zero-ambitions/
www.personalcaremagazine.com
Page 1 |
Page 2 |
Page 3 |
Page 4 |
Page 5 |
Page 6 |
Page 7 |
Page 8 |
Page 9 |
Page 10 |
Page 11 |
Page 12 |
Page 13 |
Page 14 |
Page 15 |
Page 16 |
Page 17 |
Page 18 |
Page 19 |
Page 20 |
Page 21 |
Page 22 |
Page 23 |
Page 24 |
Page 25 |
Page 26 |
Page 27 |
Page 28 |
Page 29 |
Page 30 |
Page 31 |
Page 32 |
Page 33 |
Page 34 |
Page 35 |
Page 36 |
Page 37 |
Page 38 |
Page 39 |
Page 40 |
Page 41 |
Page 42 |
Page 43 |
Page 44 |
Page 45 |
Page 46 |
Page 47 |
Page 48 |
Page 49 |
Page 50 |
Page 51 |
Page 52 |
Page 53 |
Page 54 |
Page 55 |
Page 56 |
Page 57 |
Page 58 |
Page 59 |
Page 60 |
Page 61 |
Page 62 |
Page 63 |
Page 64 |
Page 65 |
Page 66 |
Page 67 |
Page 68 |
Page 69 |
Page 70 |
Page 71 |
Page 72 |
Page 73 |
Page 74 |
Page 75 |
Page 76 |
Page 77 |
Page 78 |
Page 79 |
Page 80 |
Page 81 |
Page 82 |
Page 83 |
Page 84 |
Page 85 |
Page 86 |
Page 87 |
Page 88 |
Page 89 |
Page 90 |
Page 91 |
Page 92 |
Page 93 |
Page 94 |
Page 95 |
Page 96 |
Page 97 |
Page 98 |
Page 99 |
Page 100 |
Page 101 |
Page 102 |
Page 103 |
Page 104 |
Page 105 |
Page 106 |
Page 107 |
Page 108
