HYGIENE 10% Potassium Soap only■ 10% Potassium Soap with 0.5% coconut-derived antimicrobial active ■


40 30 20 10 0


-10 -20 -30 -40 -50


1 min after washing


1 hour after washing (1st hour)


1 min after washing


1 min after washing (2nd hour)


1 min after washing


1 hour after washing


(3rd hour) Wash Sequence


Figure 1: Transepidermal water loss data resulting from hourly hand washing using soap samples, both with and without the inclusion of a coconut- derived antimicrobial active


a powerful bactericidal agent. Its ability to effectively eliminate bacteria, especially at concentrations within the calculated range, highlights its suitability for various applications where strong antimicrobial properties are required. In conclusion, the coconut-derived


antimicrobial active exhibits promising potency as a bactericidal agent based on its MBC-to-MIC ratio. Its ability to achieve a ratio lower than 4%, as seen in its action against E.coli, emphasizes its effectiveness


in eliminating bacteria, further supporting its potential applications in diverse settings that demand robust antimicrobial capabilities.


Dermatological hypoallergenicity study for skin friendliness A rigorous dermatological hypoallergenicity study was conducted on the coconut-derived antimicrobial active, under the supervision of a dermatologist. The objective of this study was to thoroughly assess the product’s potential to trigger adverse skin reactions


when used by consumers and its likelihood of causing sensitization through repeated topical application. The clinical evaluation compared the test


product with a positive control to ascertain its skin-friendliness under conditions reflecting real-world consumer use. The assessment yielded significant results, revealing that the coconut-derived antimicrobial active demonstrated a notably low level of irritation potential. Moreover, the active was granted the designation of ‘dermatologically tested as


1 min after washing


1 hour after washing


(4th hour)


1 min after washing


1 hour after washing (5th hour)


65


www.personalcaremagazine.com


October 2023 PERSONAL CARE


% Change in TEWL


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