HYGIENE Absent ■ Slight ■ Moderate ■ Marked ■ Very marked ■ Placebo
10 9 8 7 6 5 4 3 2 1
0
10 9 8 7 6 5 4 3 2 1
0 0.5% Evosina GP Green T0-48h T28-48h SHAMPOO A - 0.5% EVOSINA GP GREEN T45-48h PLACEBO SHAMPOO
59
T0-48h 1% Evosina GP Green
10 9 8 7 6 5 4 3 2 1
0
10 9 8 7 6 5 4 3 2 1
0 Benchmark
T28-48h SHAMPOO B - 1% EVOSINA GP GREEN
T45-48h
T0-48h
T28-48h
T45-48h BENCHMARK SHAMPOO (0.5% PIROCTONE OLAMINE)
T0-48h
Figure 3: Reduction of scales after application of a placebo shampoo, shampoo with 0.5% Evosina GP Green, 1% Evosina GP Green, benchmark (rinse-off application)
Sodium usnate propylene glycol solution
was used in the trials at the concentrations 0.5% and 1%. The analyzes were taken in comparison with the same shampoo formulation containing a benchmark and the placebo shampoo. The subjects participating in the study were both female and male between 18 and 60 years, with oily and dry dandruff, itching, reddened and unbalanced sebum scalp. The specific end-point variables were
T28-48h
T45-48h
Figure 4: Reduction of scales after application of a placebo shampoo, shampoo with 0.5% Evosina GP Green, 1% Evosina GP Green, benchmark (rinse-off application). Images detected by HIROX - RX 2000 3D
analysed at baseline time (before the use of the products), after 30 minutes and 48 hours from the first use of the products and after 28 and 45 days of treatment (30 minutes and 48 hours after the last shampoo). Each group of ten volunteers used a product during hair washing on alternate days (every 48 hours) over 45 days. The flakes of dandruff were observed,
analysing their size and numerosity, at the level of the scalp and shaft; scalp redness was
clinically evaluated observing the scalp redness, analysing its intensity and extension; sebum balance was clinically evaluated observing the presence of sebum on the scalp and hair oiliness. All the variables were analysed by using
HIROX - RX 2000 3D digital microscopy system. Furthermore, when appropriate at the follow up time points, the images taken in the areas of interest by specific instruments at the different observation times were viewed and compared.
www.personalcaremagazine.com
October 2023 PERSONAL CARE
T0-30min T0-48h T01-30min T01-48h T28-30min T28-48h T45-30min T0-30min T0-48h T01-30min T01-48h T28-30min T28-48h T45-30min T45-48h T0-30min T0-48h T01-30min T01-48h T28-30min T28-48h T45-30min T0-30min T0-48h T01-30min T01-48h T28-30min T28-48h T45-30min T45-48h T45-48h T45-48h
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