NEWS 7
Air pollution linked to hair loss
Research presented at the 28th EADV Congress in Madrid shows, for the first time, that exposure to common air pollutants known as particulate matter (PM) is linked to hair loss in humans. The research was conducted by exposing cells from the human scalp at the base of hair follicles, known as human follicle dermal papilla cells (HFDPCs), to various concentrations of PM10-like dust and diesel particulate. After 24 hours the researchers performed a scientific
process, known as western blotting, to detect the levels of specific proteins in the cells. The results showed that the presence of PM10 and diesel particulate decreased levels of β-catenin, the protein responsible for hair growth and morphogenesis. The study also revealed that the levels
of three other proteins (cyclin D1, cyclin E and CDK2), which are responsible for hair growth and hair retention, were decreased by PM10-like dust and diesel particulate in a dose dependent manner, meaning that the greater the level of pollutant, the greater the decrease in proteins was found.
Lead researcher, Hyuk Chul Kwon from T 1 month
the Future Science Research Centre in the Republic of Korea, said: “While the link between air pollution and serious diseases such as cancer, COPD and CVD are well established there is little to no research on the effect of particular matter exposure on the human skin and hair in particular. Our research explains the mode of action of air pollutants on human follicle dermal papilla cells, showing how the most common air pollutants lead to hair loss.”
Investment in powder production
Silab is commissioning its new powder production unit on its site. The company selected the spray-drying technology to transform its active ingredients into a dry form, marketed without preservatives. Commissioned in September 2019,
this production plant complies with the pharmaceutical Good manufacturing practices (GMP). This guarantee, combined with highly innovative process engineering and packaging in controlled- atmosphere areas, enables production of powders with stringent bacteriological standards.
Xavier Gaillard, deputy general manager for Strategy, said: “We are proud of having carried out this major project that required an investment of €11 million and that was supported by the European Union, the French government, the Nouvelle-Aquitaine region, and the Corrèze departmental council. Bringing this production technology in house will allow us to offer our active ingredients in preservative-free powderform. This fits into a strategy of
November 2019 PERSONAL CARE ASIA PACIFIC
diversifying our cosmetics offerings (Silab Cosmetics), while meeting the current expectations of medicalising skin care (Silab Softcare).” The project led to the creation of several jobs (around ten expected in the long term) and the development of new skills in house.
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