ANTI-AGEING 21 T=28 D Placebo cream 0 -1.2% -5 -10 -15 -20 -25 *** p<0.001 Figure 8: Skin firmness and elasticity.
(average of 15% with a maximum of 57%), greatly increasing the skin elasticity.
Skin thickness: (Aloka alpha6 pro-sound ultrasound machine, Hitachi) The skin thickness was measured by ultrasound, observing that there is an increase of it, up to 26% at 56 days, with a stratum corneum visibly strengthened and a re-densified skin.
Clinical evaluation of wrinkles (crow’s feet):
Depth and volume, and skin roughness, (Ra parameter)
l Depth: The active significantly reduced wrinkle depth at 28 days (an average of 19% with a maximum reduction of 37%) and at 56 days (21% on average, with a maximum reduction of 41%)
l Volume: The active significantly reduced the wrinkle volume at 28 days (average of 8% with a maximum reduction of 33%) and at 56 days (13% average, and maximum
reduction of 38%)
l Skin Roughness: The active significantly reduced the skin roughness at 28 days (average of 3%, up to 10% reduction), and at 56 days (with an average of 6% and up to 18% reduction)
l Skin profilometry (PRIMOS 3D, GFMesstechnik GmbH) and digital images: The images show an improvement of skin complexion, a more even texture and a clear reduction of wrinkles.
-17% ***
-4.6%
Cream with 1% Olea VitaePLF
T=56 D Placebo cream
Cream with 1% Olea VitaePLF
20 15 10 5 0
-5 -10
-20% ***
-7%
*** p<0.001 **p<0.01
T=28 D *** +16% T=56 D
+15% **
Placebo cream -0.5%
Placebo cream
Cream with 1% Olea VitaePLF
Cream with 1% Olea VitaePLF
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dow.com November 2019 ® and ™ are Trademarks of The Dow Chemical Company © 2019
PERSONAL CARE ASIA PACIFIC
Decrease in Uf (vs initial time)
Increase in Ur/Ue (vs initial time)
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