oncolog-hematolog
ro
şi alte mecanisme ale carcinogenezei care consecinţă a prezenţei unei vechi boli n prevenţia primară la grupele de risc
diferă faţă de cancerul colorectal sporadic inflamatorii intestinale. din populaţia generală - risc general prin
- pierderea heterozigoţiei cromozomului 6 Importanţa tuturor factorilor de risc evitarea sau tratarea factorilor de risc de
este un element caracteristic în cancerul amintiţi nu este nicidecum una pur mediu;
colorectal asociat cu colita ulcerativă. teoretică, ci mai ales una de interes practic. n terapia genică în cazul cancerului co-
Aceasta presupune prezenţa unei gene Tratamentul curativ al cancerului de colon lorectal nu mai este astăzi de domeniul
supresoare la nivelul cr 6, a cărei mutaţie prevede trei aspecte importante: viitorului îndepărtat, ci al prezentului în
se află în legătură cu dezvoltarea colitei n tratamentul preventiv în cazul afec- ţările civilizate; de aceea, cunoaşterea
ulcerative. Cancerul colorectal reprezintă ţiunilor genetice este esenţial - rezecţie mecanismului epigenic al tumorogenezei
o importantă şi uneori ameninţătoare chirurgicală; devine deosebit de importantă. n
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