LIFESTYLE COSMETICS 85 a b c


Caper Buds


Caper Fruit


Caper Fruit


Processed


Caper Buds


Mulberry Leaves


Rose Roots


HerbaGlow NRG


HerbaGlow NRG


Long-term (40°C,


3 months)


Figure 3: A synergistic and stable blend of energising metabolites. (A) HPTLC fingerprint of different caper-based extracts. (B) Illustrative, exhaustive extraction with methanol of caper buds, mulberry leaves and rose roots. The active ingredient concentrates these molecules in a natural solvent system. (C) Fingerprints of the active ingredient upon different stress conditions.


salidroside are well reported to stimulate mitochondrial function and to protect them against stress-induced dysfunction by activating ROS removing enzymes.22


Phytochemical analysis Objective To identify the main metabolites and to evaluate their stability.


a b Technique


HPTLC (high performance thin layer chromatography) was used to assess the overall flavonoid/ phenolic compound composition.


Results


The comparison of different caper extracts demonstrated that the active ingredient is


based on optimal starting material, i.e. high-quality caper flower buds. Of note, unprocessed caper buds contain the highest amount and the most versatile profile of valuable metabolites (Fig 3A). Each plant contributes particular lead compounds in order to form an efficient cocktail of mitochondria-activating molecules. The presence of substantial


Heat (80°C, 2h)


150


* * +19% 100


50 Untreated Resveratrol 0.1% HerbaGlow NRG


Figure 4: Boosting the numbers of mitochondria per cell. (A) Typical images of skin cells with low and high mitochondria numbers (top and bottom, respectively). The green fluorescence represents mitochondria; the nuclei are depicted in blue. (B) Human skin cells were incubated with 20 ug/ml Resveratrol (positive control23


) or active ingredient. N = 12 from two independent experiments; Mean + SEM; Student’s unpaired t-test versus untreated control; * = p < 0.05. November 2018 PERSONAL CARE EUROPE


Mitochondria Number (%)


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