SUN CARE 55


Formulation 2: Sunscreen Formula without using AvoBrite: Phase Tradename


A HallBrite EZ-FLO TDX NO HallBrite BHB


HallStar GMS SE/AS HallStar GMS PURE HallStar TA-1618 Olivem 800 Tween 60


SP-10 Kobo SP-10 Kobo


B INCI Name (INN/SAN) (Other Information)


Butyloctyl Salicylate, Titannium Dioxide(nano), Triceteareth-4 Phosphate, Dimethicone Crosspolymer, Silica


Control polymer Butyloctyl Salicylate


Glyceryl Stearate, PEG-100 Stearate Glyceryl Stearate Cetearyl Alcohol


Ceteareth-6 Olivate Polysorbate 60


Nylon 12 Nylon 12


GalSORB Avobenzone Butyl Methoxydibenzoylmethane [Avobenzone] EDTA-2Na D.I-Water


Disodium EDTA Water


C


Olivem 1000 Xanthan gum


D


E F


1,3-Butylene glycol 1,2-Hexanediol Trienthanolamine Water D.I. Parsol HS DC 345


Cetearyl Olivate, Sorbitan Olivate Xanthan gum


1,3-Butylene glycol 1,2-Hexanediol Trienthanolamine Water D.I.


Phenylbenzimidazole Sulfonic Acid Cyclopentasiloxane, Cyclohexasiloxane


modifying the electronic environment of the UV filter molecules so that they can return to their ground states more effectively. Butyloctyl Salicylate, the prototypal Hallstar product HallBrite®


BHB, works by this


mechanism. The second mechanism involves the photostabiliser accepting the excited state energy from the UV filter molecule and then quickly releasing this energy via non-radiative decays. We will


use our most recently developed photostabiliser product, Acrylates Copolymer (AvoBriteTM


% Wt 6.00


6.00 6.00 2.00 1.00 1.00 1.00 0.50 1.00 1.50 3.00 0.05


22.65 3.00 0.3


3.00 1.00 3.00


30.00 6.00 2.00


Methoxydibenzoylmethane (BMDBM)) is one of the most effective UVA filters and the only one accepted in the global market. Unfortunately, it is unstable when exposed to UVR. The photodegradation reaction of the BMDBM molecule has been thoroughly studied by Hallstar and others; these studies are widely available in the open literature, so we will not discuss the reaction further. As the desire for UVA protection grows, stabilising avobenzone provides a universal approach to improving UVA protection performance. While designing our newest


), as an example to


illustrate the design principles and effectiveness of this technology.


Protecting UV filters against photodecomposition: increase filter efficiency Avobenzone (INCI: Butyl


UV spectrum and SPF/PFA comparison of sunscreen films from the above formulation after 10 minutes simulated sunlight irradiation (equals to about 1 hour of middle day sun exposure in the Mediterranean region)


UV spectrum comparison of sunscreen films with and without using AvoBrite


1.4 1.2 1


0.8 0.6 0.4 0.2 0


290 302 314 326 338 350 362 374 386 398 Figure 3: Sunscreen formulation with and without using AvoBrite and their performance comparison. November 2018 PERSONAL CARE EUROPE


n Before UV irradiation n After UV irradiation


120 100 80 60 40 20 0


Sunscreen using AvoBriteTM


Sunscreen without using AvoBriteTM


SPF and PFA performance measured after irradiation of the two sunscreen formulas


SPF and PFA Comparison


photostabilisers, Hallstar focused on the triplet excited states of avobenzone. First, we measured the triplet excited state energy levels of both the enol and keto structures of avobenzone. Next, we designed many possible quencher structures with the right energy levels, so they could accept the excited state energy from avobenzone. Several representative structures are included in Figure 1 with the triplet state energies of avobenzone. We then used laser flash photolysis to accurately measure the quenching rate constant of avobenzone by the different quencher structures. Representative results and structures are shown in Figure 2. Acrylates Copolymer ingredient incorporates the most effective quencher structures from this study. The effectiveness of Acrylates Copolymer was demonstrated in a sunscreen formulation (Figure 3). By making avobenzone more stable and efficient, Acrylates Copolymer provides formulations with much better sun protection performance.


Protecting UV filters against ROS generation: increase safety and effectiveness


Semiconducting metal oxides such as TiO2 n SPF n PFA


Page 1  |  Page 2  |  Page 3  |  Page 4  |  Page 5  |  Page 6  |  Page 7  |  Page 8  |  Page 9  |  Page 10  |  Page 11  |  Page 12  |  Page 13  |  Page 14  |  Page 15  |  Page 16  |  Page 17  |  Page 18  |  Page 19  |  Page 20  |  Page 21  |  Page 22  |  Page 23  |  Page 24  |  Page 25  |  Page 26  |  Page 27  |  Page 28  |  Page 29  |  Page 30  |  Page 31  |  Page 32  |  Page 33  |  Page 34  |  Page 35  |  Page 36  |  Page 37  |  Page 38  |  Page 39  |  Page 40  |  Page 41  |  Page 42  |  Page 43  |  Page 44  |  Page 45  |  Page 46  |  Page 47  |  Page 48  |  Page 49  |  Page 50  |  Page 51  |  Page 52  |  Page 53  |  Page 54  |  Page 55  |  Page 56  |  Page 57  |  Page 58  |  Page 59  |  Page 60  |  Page 61  |  Page 62  |  Page 63  |  Page 64  |  Page 65  |  Page 66  |  Page 67  |  Page 68  |  Page 69  |  Page 70  |  Page 71  |  Page 72  |  Page 73  |  Page 74  |  Page 75  |  Page 76  |  Page 77  |  Page 78  |  Page 79  |  Page 80  |  Page 81  |  Page 82  |  Page 83  |  Page 84  |  Page 85  |  Page 86  |  Page 87  |  Page 88  |  Page 89  |  Page 90  |  Page 91  |  Page 92  |  Page 93  |  Page 94  |  Page 95  |  Page 96  |  Page 97  |  Page 98  |  Page 99  |  Page 100  |  Page 101  |  Page 102  |  Page 103  |  Page 104