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SKIN CARE 45 4


n Placebo n Active 4%


0 -4 -8 ** -12 D29 * D84


Figure 5: Application of an emulsion with 4% active significantly reduces skin blueness. The b* value measurement revealed a reduction in skin blueness of 3% after 29 days and 7.2% after 84 days. The effect after 84 days was significant over baseline and placebo. The statistical values in blue relate to the comparison of active with the placebo, whereas the black values relate to the comparison with the initial condition. Wilcoxon signed-rank test.


better on day 29 and day 84 than at the beginning of the study (improvement of 1.3 % and 5.3 % respectively; Fig 2). Additionally, the treatment after 84 days showed significantly better results even as compared to the placebo treatment, which did not produce a beneficial effect. The maximum height of the roughness profile (Rz) measurement showed an improvement of 1.3% after 29 days and 4.9% after 84 days respectively (data not shown), which is in agreement to the previously mentioned data.


Dark circles


The skin colour change was addressed by conventional chroma meter measurement. It revealed that application of 4% active had a


significant lightening effect on the eye area, increasing over time (Fig 3). The results revealed a significant enhancement over baseline and placebo. Additionally, skin redness was significantly


reduced during treatment with 4% active. The results showed a reduction of 8.7% after 29 days and 7.3% after 84 days (Fig 4). In addition to this, skin blueness was reduced strikingly during treatment with 4% active. The results showed a reduction of 3% after 29 days and 7.2% after 84 days (Fig 5). In summary, the lightening effect combined with the reduction of the skin redness and blueness reveal an obvious improvement in the eye area appearance, which can be seen from Figure 6.


Mean + SEM n=20; * = p<0.05 ** = p<0.01


Photographic documentation To underline the results obtained, macro photographs were taken. Figure 6 shows a representative image of subject number 21 at the beginning of the study and after 84 days of treatment with 4% active. The overall eye appearance was improved. Particularly noteworthy is the reduction of the visibility of capillary veins, which stand out through the delicate skin in the periorbital region (lower black arrows). Additionally, the dark skin regions are visibly lighter (upper black arrows).


Discussion and conclusion Today’s insanely fast-paced world combined with unhealthy lifestyle choices leave their visible traces, in particular, around our eyes. Dark circles and puffy eyes can make even the most dynamic people look dull and tired. Sleep problems, allergies, exhaustion or inherited features are just some of the factors responsible for dark circles and swollen eyes. In general, in the advanced ageing process, the tissue and muscles surrounding the eyes weaken, and protruding fat tissue contributes to the swollen appearance. Sooner or later, time or better said long days and restless nights take their toll. Concealers may camouflage the darkness under your eyes but unfortunately, they cannot addresss the problem of a swollen eye area. For this, it is necessary to analyse and treat the problem at its roots. Rahn has developed Slimexir to tackle the problem of fat excess, fluid retention and sagging skin. Application of Slimexir may significantly reduce discolouration and puffiness in the eye area. The overall eye appearance is visibly


The dermosoft®


multifunctional additives with


antimicrobial properties


Two product lines, two ways


to product safety. The Verstatil®


safe, reliable and economic


preservation systems range:


range:


November 2018


PERSONAL CARE EUROPE


Relative to initial condition (%)


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