ORL
ro
laringologie
Figure 2. S100 protein
trate was absent (0), rare lympho-
positive cell, dendritic
cytes (+1), high density (+2), lym-
morphology (a, x400).
phoid tissue (+3). Inflammatory
Leucoplasia, S100
infiltrate index represented lesion
protein positive cell
category cases mean value.
suprabasal distribu-
tion (b, x400). In situ
Results
carcinoma - small
S100 protein positive cells were
number of positive cells
identified in all cases of squamous
(c, x400). S100 protein
cell carcinoma, being absent in the
positive cells – well
case of adenoid cell carcinoma. APC
differentiated squamous
presented medium dimensions, with
cell carcinoma (d, x400).
numerous relative long dendritiform
Numerous positive cells
cytoplasm extensions ( fig.2a). Their
between keratosic pearl
number varies with lesion type and
epithelial cells (e, x400).
grading. In cases of leukoplasia the
number and morphology of S100
protein positive cells were similar
lated dendrites were excluded. Lucia Images were recorded in JPEG for- with squamous stratified epithelium
G (Nikon) soft has counted positive mat and processed by microscopic (mean in epithelial area 12.66/field
signals, by choosing for each case image analyser. The presence of x400); positive cell body was localised
3 fields of tumour and peritumour APC was correlated with lymphoid- in epidermis suprabasal level, heav-
cells islands and cordons with maxi- monocitar infiltrate presence and ing extensions through surface and
mum density of positive cells. density. Lymphoid-monocitar infil- lamina propria ( fig.2b). In case of in
pag. 30
Nr. 2/februarie 2009
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