MARINE INGREDIENTS Volunteer 1
250 200 150 100 50 0
T0 T14
Micrococcus spp. ■ Staphylococcus spp. ■
8.000 6.000 4.000 2.000 0
Volunteer 2 T0 T14
Micrococcus spp. ■ Staphylococcus spp. ■
250 200 150 100 50 0
Volunteer 3 T0 T14
Bacillus spp. ■ Kocuria spp. ■ Staphylococcus spp. ■
2.000 1.600 1.200 800 400 0
Volunteer 4
71
T0
T14
Corynebacterium spp. ■ Staphylococcus spp. ■
Figure 8: Aerobic microbiota composition variation of the different aerobic microorganisms composing face skin microbiota observed on the skin of some volunteers with the use of the active formulation
is identified by MALDI-TOF MS, to evaluate if the cosmetic treatment had an effect not only in the absolute amount, but also in the composition and relative abundance of the different genera of microorganisms forming face skin microbiota (Figure 8). The treatment with the active formula
preserves the composition and relative abundance of the different microorganisms composing face skin microbiota, since no evident dysbiosis related to the active cosmetic treatment was visible under the applied conditions. The Nannochloropsis extract has excellent microbiota-balancing and microbiota-nourishing properties for dry skin, while respecting the individual microbiome.
The future of skin health starts from perinatal and early post-natal period Early life is a critical period for establishment of both the microbiome and immune responses, with long term implications for health. Recent studies suggest that the cutaneous microbiome composition in neonatal life is crucial in shaping adaptive immune responses to commensals, and that disrupting these interactions might have lasting health implications.5 After birth, during barrier development,
impaired skin function makes the skin vulnerable to chemical damage, microbial infections, and skin diseases, possibly compromising the general health of the infant. Compared to an adult skin, the baby
skin is thinner, more delicate and reacts more sensitively to external aggressors. Then, the skin tolerance, on baby skin, of
the Nannochloropsis extract was assessed by measurement of its effects on tissue viability and inflammatory response on a three-dimensional immature model, mimicking a baby’s skin. A standard RHE model, according to OECD
439, is a 17 day-old tissue culture and is considered as a mature epidermis. To assess the skin tolerance on a ‘baby skin’, the use of immature RHE, with only ten day-old tissue cultures, has been selected, allowing to obtain less differentiated tissues with a greater skin sensitivity than that of standard tissues. The Nannochloropsis extract has been topically applied undiluted to this immature
www.personalcaremagazine.com
May 2024 PERSONAL CARE
Microbiota count's by colony, CFU/cm2
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