52 TRENDING TECHNOLOGIES
more suitable for specific skin types. For example, nanocarriers with oil-control effects can be selected for oily skin, while those with moisturizing effects can be chosen for dry skin. This personalized skin care approach better
meets consumer needs and enhances the market competitiveness of products.
Reduced irritation and allergies Nanocarrier delivery technology can achieve slow and controlled release of active ingredients, avoiding skin irritation and allergies caused by large amounts of sudden release. At the same time, nanocarriers can reduce
direct contact between active ingredients and the skin, thus reducing their irritation and allergenicity.
Improved safety and effectiveness of products Nanocarriers can achieve targeted delivery, accurately delivering active ingredients to the target site while avoiding damage to normal cells.
This precise delivery method not only
improves product safety but also enhances its effectiveness.
Innovative product forms Nanocarrier delivery technology brings innovative product forms to the cosmetics industry. For example, liquid or solid skincare products prepared using nanotechnology can be easier to use and carry. Additionally, nanocarriers can be combined with smart technology to develop intelligent cosmetics that can monitor skin conditions in real-time and automatically adjust product formulations.
Cosmetics applications Lipid vesicles, also known as liposomes, are
Polar heads facing hydrophilic region
Hydrophobic drugs localised in the hydrophobic Iamella
Hydrophilic drug localised in aqueous region encapsulated
Non-polar tails facing each other to form a hydrophobic region
Figure 1: Structure of niosomes
nanocarriers with a special vesicular structure formed by self-assembly of amphiphilic lipid molecules in a solution. Based on the vesicular structure, they can be classified into unilamellar vesicles, multilamellar vesicles, and multivesicular vesicles. Depending on the membrane material
of the vesicles, they are further categorized into phospholipid vesicles (traditional liposomes), non-ionic surfactant vesicles (flexible liposomes/transfersomes, Niosomes/ Transfersomes), polyol vesicles (ethosomes), and block polymer vesicles (analogous liposomes), as shown in Figure 1.3
AC-Ceramide NP SANIO Ceramide NP is a new generation skin moisturizer developed in recent years.
It can promote the renewal of the skin’s natural protective layer, form an effective transepidermal water loss barrier, and repair sensitive and dry skin. Currently, it has been applied as an
effective skin care active ingredient in skincare cosmetics. Ceramide NP is a highly crystalline substance with low solubility and poor water dispersibility, which tends to crystallize and precipitate during storage. Therefore, Aneco has developed a new,
stable Ceramide NP transdermal delivery carrier to effectively exert its skin care benefits.4 The microscopic morphology of Ceramide
NP SANIO is observed using transmission electron microscopy, as shown in Figure 2. The Ceramide NP SANIO exhibits a uniform spherical shape, and the particle size is similar to the results measured by the laser particle size analyzer.
The addition of the polymer capric/caprylic
triglyceride polyethylene glycol glycerides embeds branches on the surface of the liposomes, effectively preventing liposome particle aggregation and enabling stable dispersion in aqueous media. Figure 3A and 3B show the particle size,
PDI, and Zeta potential, respectively. The data indicate that the liposomes have a uniform particle size distribution and high stability. After being stored for one year, there is no significant change in the particle size, and the product appearance remains without precipitation, indicating good liposome quality.
Figure 2: Transmission electron microscopy images showing the microscopic morphology of Ceramide NP SANIO
PERSONAL CARE May 2024
AC-EUK-134 SANIO 0.5% Niosome is a form of amphiphilic molecular ordered assemblies, which consists of spherical or ellipsoidal single- or multi- chamber structures formed by enclosed bilayer molecules. On one hand, niosomes have excellent elasticity and deformability, enabling them to penetrate the stratum corneum of the skin, scientifically target the deep layers of the epidermis, and have higher skin penetration efficiency than liposomes.
www.personalcaremagazine.com
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