ANTI-AGEING
the Nasturtium officinale extract significantly boosts the synthesis of the receptor CB1R and of filaggrin by 46% and 25% respectively. These effects were confirmed in vivo with the improvement of skin quality of young and mature Caucasian volunteers. After five days of twice daily application, the
Nasturtium officinale extract at 2% improves the quality of the skin barrier of young and mature Caucasian volunteers by limiting water losses by 4.4% and 9.5% respectively. Hydration of the facial skin of young and
mature Caucasian volunteers is also boosted by 12.7% and 12.9% respectively. Finally, the characteristic parameters of complexion radiance were assessed by visual scoring by trained evaluators using digital photos. The results show a global improvement in
young and mature Caucasian volunteers: the complexion is more luminous, fresher and the healthy-glow appearance is increased by reducing olive colour and the state of eye fatigue (significant effects compared to the placebo) (Figure 5). The effects on the barrier function, hydration and complexion radiance intensify after 28 days of treatment.
Conclusion Silab has beneficially used the mineral richness of watercress to develop Myoline, its latest relaxing active ingredient. Faithful to its responsible strategy, the company has favored a local, traceable, and environmentally friendly sourcing. The authentication of the raw material was carried out using the molecular barcoding technique, thus securing the supply. With its myorelaxing (action on the
neuromuscular junction) and wellness effects (promotion of the expression of stress response mediators and receptors), this Nasturtium officinale extract acts as a genuine plant ‘Botox- like’; within five days of use, expression lines on young and mature volunteers are reduced. The skin’s barrier function is also reinforced,
for rapid and long-lasting moisturizing and radiance-boosting effects. Thanks to this unique dual action, this natural active ingredient counteracts the deleterious behavioural and biological consequences of stress on the skin, leaving it visibly younger and more radiant. Recommended at 0.5% to 2.0% in
formulation, Myoline is available in an aqueous solution. With a natural origin content of 99.2%, this natural active ingredient complies with international cosmetic regulations (Europe, United States, China, Japan etc.). It is easy to formulate in face care formulations.
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5. Denda et al. Stress alters cutaneous permeability barrier homeostasis. Am. J.
www.personalcaremagazine.com
D0, before treatment Reflection: +
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6. Maarouf et al. The impact of stress on epidermal barrier function: an evidence-based review. BJD. 2019; 181: 1129-1137
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8. Todorova et al. Oxytocin receptor-mediated proliferation of the basal epidermal layer in human skin explants after mechanical stimulation. Poster, 50th Annual Meeting of the European Society for Dermatological Research. 2021
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Nasturtium officinale extract at 2% Reflection: +++
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Figure 5: Visualization of the effect of Nasturtium officinale extract on complexion radiance in young Caucasian volunteers
receptor signaling and bias. Cannabis and Cannabinoid Research. 2017; DOI: 10.1089/ can.2016.0037
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May 2024 PERSONAL CARE
43 Result(s)/Silab retouched photo: ***: P < 0.001 --- *: P < 0.05 --- ns: non-significant
Figure 4: Evaluation of the ‘soft focus’ effect of the Nasturtium officinale extract by untrained evaluators after five and 28 days of twice daily application by the young Caucasian panel
YOUNG PANEL
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