56 TRENDING TECHNOLOGIES
Mānuka: unleashing New Zealand’s biodiversity
Andrea Taimana, Sylvester Kuo – Organic Bioactives
The bountiful biodiversity and rich cultural tapestry of New Zealand is interwoven with the healing traditions of the indigenous Māori people, who have long revered the mānuka tree (Leptospermum scoparium) for its myriad medicinal properties. Mānuka has long been recognized for its medicinal properties, particularly in the form of honey. However, the lesser-known yet equally potent source lies in its leaves. Recent studies have delved into the
bioactive compounds present in mānuka leaves, unravelling a treasure trove of cosmetic applications potential. Among these compounds, β-caryophyllene has emerged as a key player in conferring anti-inflammatory properties to the mānuka leaf. This article explores the unique bioactive compounds found in mānuka leaves, with a special focus on β-caryophyllene and its role in combating inflammation. New Zealand-based Organic Bioactives
proudly presents a novel ground-breaking cosmetic active – MānukaDerMX® - hereafter, the mānuka leaf extract, promising high- efficacy in skin, scalp, and hair care. This article delves into the unique attributes of mānuka leaf extract, exploring its potent antimicrobial, antioxidant, and anti-inflammatory properties for skin scalp and hair and sustainable harvesting practices deeply rooted in Māori tradition.
PERSONAL CARE May 2024
CH3
H2
C
H Figure 1: Cryophyllene structure
Mānuka leaf and its rich bioactive composition Mānuka, a native shrub of New Zealand, has been traditionally used by indigenous communities for various medicinal purposes. These compounds not only contribute to the plant’s resilience but also offer a myriad of health benefits. Mānuka leaves contain a diverse array
of bioactive compounds, contributing to its medicinal properties. While the exact number can vary, numerous studies have identified and characterized most beneficial bioactive compounds in mānuka leaves.
CH3
CH3 H
Key bioactive compounds ■ β-Caryophyllene: A sesquiterpene with anti- inflammatory properties, selectively binding to cannabinoid receptor type 2 (CB2) in the endocannabinoid system. ■ Flavonoids: These are a group of polyphenolic compounds with antioxidant and anti-inflammatory effects. Examples include quercetin, kaempferol, and myricetin. ■ Tannins: Polyphenolic compounds known for their astringent properties, contributing to anti-inflammatory and antimicrobial effects. ■ Polyphenols: Various polyphenolic compounds, such as gallic acid and catechins, with antioxidant and anti-inflammatory properties. ■ Leptospermone: A compound with antimicrobial properties, contributing to the plant’s defence mechanisms. ■ Phenolic acids: Compounds like caffeic acid and chlorogenic acid, known for their antioxidant and anti-inflammatory effects. ■ Terpenoids: Diverse terpenoid compounds with potential therapeutic benefits, including anti-inflammatory and antimicrobial activities. ■ Alkaloids: Though present in smaller quantities, alkaloids contribute to the overall bioactivity of mānuka leaves. It is important to note that the relative
concentrations of these compounds can vary based on factors such as plant age,
www.personalcaremagazine.com
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