MARINE INGREDIENTS


75


60 50 40 30 20 10 0


Increased 53.4%


50.2 32.7


20 15 10 5 0


Day 0 Day 28


17.8 14.6


Lowered 17.6%


Day 0


Day 28 Figure 3: The proliferation of fibroblasts and keratinocytes after treatment with 0.025%, 0.05%, 0.1% and 0.2% red grape algae extract (Ctrl = control)


keratinocytes proliferation compare to control group. Specifically, 0.025% and 0.05% red grape algae extract can promote a 23% increase in fibroblasts and keratinocytes proliferation, respectively. The results demonstrate that red grape


algae extract possess powerful anti-allergic and anti-inflammatory effects, providing noticeable soothing effects on the skin. Additionally, the proliferation of fibroblasts enhances the synthesis of collagen, thereby slowing down skin ageing and the formation of wrinkles. Simultaneously, the proliferation of keratinocytes contributes to repairing


damaged epidermis, improving the skin barrier, and consequently mitigating the ageing process of the skin.


Multipurpose benefits in in vivo studies Following the above mentioned in vitro studies, the benefits of red grape algae were further complemented by the findings of in vivo efficacy tests.


Skin hydration and soothing properties This study included 32 healthy women volunteers with sensitive skin (lactic acid


irritation score ≥ 3), poor facial barrier function, and some redness. The participants applied 2% red grape algae extract serum for 28 days. Stratum corneum hydration and


transepidermal water loss are widely-used indices for evaluating skin barrier function. These indices were measured at the outset (Day 0) and on Day 28. A significant enhancement in stratum corneum hydration was observed following 28 days of continuous application of 2% red grape algae extract serum, which was 53.4% higher compared with that on Day 0. Transepidermal water loss reduced by 17.6%


www.personalcaremagazine.com


March 2024 PERSONAL CARE


Stratum Corneum Hydration


Transepidermal Waterloss (g/m2h)


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