ANTI-POLLUTION 85 aging. J Invest Dermatol. 2010;130:2719–2726
3. Krutmann J, Liu W, Li L, Pan X, Crawford M et al. Pollution and the skin: from epidemiological and mechanistic studies to clinical implications. J Dermatol Sci. 2014;76:163–168
4. Pan TL, Wang PW, Aljuffali IA, Huang CT et al. The impact of urban particulate pollution on skin barrier function and the subsequent drug absorption. J Dermatol Sci. 2015;78:51–60.
5. Mancebo SE, Wang SQ. Recognizing the impact of ambient air pollution on skin health. J Eur Acad Dermatol Venereol. 2015;29(12):2326–2332
6. Calabró V, Garcés M, Càceres L et al. Urban air pollution induces alterations in redox metabolism and mitochondrial dysfunction in mice brain cortex. Arch Biochem Biophys. 2021
7. Sgarbossa A, Dal Bosco M, Pressi G, Cuzzocrea S et al. Phenylpropanoid glycosides from plant cell cultures induce heme oxygenase1 gene expression in a human keratinocyte cell line by affecting the balance of NRF2 and BACH1 transcription factors. Chem Biol Interact. 2012;199:87–95
8. Natarajan VT, Singh A, Kumar AA, Sharma P et al. Transcriptional upregulation of Nrf2dependent phase II detoxification genes in the involved epidermis of vitiligo vulgaris. J Invest Dermatol. 2010;130:2781–2789
9. Furue M, Takahara M, Nakahara T, Uchi H. Role of AhR/ARNT system in skin homeostasis. Arch Dermatol Res. 2014;306:769–779
10. Done AJ, Gage M, Nieto NC, Traustadóttir T. Exerciseinduced Nrf2 signalling is impaired in aging. Free Radic Biol Med. 2016;96:130–138
11. Narasimhan M, Rajasekaran NS. Exercise, Nrf2 and antioxidant signaling in cardiac aging. Front Physiol. 2016;doi:10.3389/fphys.2016.0024
12. De Benedetto A, Rafaels NM, McGirt LY, Ivanov AI et al. Tight junction defects in atopic dermatitis. J Allergy Clin Immunol.
Skin is less dull Skin is purified Skin tone is fresher 93% 87% 91% 78% 82% T15 min T2 weeks Skin firm
Skin is energized and revitalized
91% skin fatigue Reduced 87% 96% 89% 77% T15 min T2 weeks
Figure 4: Self-assessment of skin tone (top) and rejuvenation (bottom) by volunteers from Guangzhou 2011;127:773–786
13. Leung DYM, Berdyshev E, Goleva E. Cutaneous barrier dysfunction in allergic diseases. J Allergy Clin Immunol. 2020;145:1485–1497
14. Zheng Y, Hunt R, Villaruz A, Fisher EL et al. Commensal Staphylococcus epidermidis contributes to skin barrier homeostasis by generating protective ceramides. Cell Host Microbe. 2022;30:301–313
15. Asselineau D, Bernhard B, Bailly C, Darmon M.
Epidermal morphogenesis and induction of 67kD keratin polypeptide by culture of human keratinocytes at the liquid–air interface. Exp Cell Res. 1985;159:536–539
16. NASA Climate. Vanishing corals part two: climate change is stressing corals but there’s hope.
https://climate.nasa.gov/explore/ask- nasa-climate/3290/vanishing-corals-part- two-climate-change-is-stressing-corals-but- theres-hope/
89% 83%
Skin is softer 94% 90% 89% Skin looks younger
91% 87%
Skin is more hydrated 95% 90% 92%
Skin tone is more radiant
www.personalcaremagazine.com
May 2026 PERSONAL CARE MAGAZINE
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