NEWS


JAKA Biotech gives global debut to neuro-soothing ingredient


JAKA Biotech gave a global debut to Gavient PY, its neuro-soothing skin care active ingredient, at the PCHi 2026 trade show in Hangzhou, China. Gavient PY targets the excessive


activation of TRPV1/TRPV4 channels in keratinocytes, thus reducing glutamate overproduction at the source. Meanwhile, it inhibits glutamate


receptor activation in neuron-like cells to block abnormal signal transmission of nerve impulses. During the development process,


innovative biological models of cell-to-cell communication and ‘glutamatergic neurotransmission


Syensqo brews coffee-based scalp care active


Syensqo launched Re2 Coffea Arabica Peptide, a novel, clinically proven scalp care active derived from coffee grounds, at in-cosmetics Global 2026 in Paris, France. The ingredient leverages


proprietary molecular docking technology to selectively extract targeted peptide fragments that helps soothe the scalp, boost hydration, reinforce barrier function and reduce hair loss by over 80%. In addition to Re2 Coffea


Arabica Peptide, Syensqo introduced new science-based solutions that unlock fresh opportunities for formulators in skin and hair care. Cerafy Clear NP Boost is an


innovative ceramide-loaded liposome delivery system, uniquely designed to enhance ceramide release into the skin. Dermalcare Velvet is a plant-


based polymeric emollient and natural alternative to lanolin, suitable for baby care, skin care, makeup and sun care. Polycare Split Therapy SGI


is a biobased polymer sourced from Syensqo’s Sustainable Guar Initiative (SGI) that seals up to 90% of split ends after a single use.


www.personalcaremagazine.com May 2026 PERSONAL CARE MAGAZINE


functionality’ were constructed for the first time. In vitro tests show that Gavient PY


can significantly inhibit the abnormal activation of TRPV4, TRPV1, PAR2, and HRH1 receptors at extremely low doses. In neuron-like cell model, Gavient


PY can effectively suppress the activation of glutamate receptor activation, simultaneously down- regulate glutamate release, and block abnormal signal transmission of nerve impulses.


enhance the skin’s tolerance to external irritants. Shanghai-based JAKA Biotech


In clinical tests, both lactic acid stinging and capsaicin stimulation models show that Gavient PY at a dosage of 0.1% can rapidly relieve skin discomforts caused by external stimuli within five minutes. Long-term use can significantly


also showcased Lumiroot GD, its newly launched whitening ingredient. Its core component is glabridin, a classic and widely recognized whitening ingredient. Clinical tests have shown that


Lumiroot GD can rapidly reduce the skin’s melanin index (MI value) and increase the skin’s ITA° value within seven days, significantly improving skin brightness within 14 days.


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